Titanium Powder Sintering for Preparation of a Porous FGM Destined as a Skeletal Replacement Implant

Thieme, Michael; Wieters, K.-P.; Bergner, F.; Scharnweber, Dieter; Worch, H.; Ndop, J.; Kim, T.J.; Grill, Wolfgang

doi:10.4028/www.scientific.net/msf.308-311.374

Cited by 71 publications

(80 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, critical problems caused by the mismatch of Young's modulus between implant (110 GPa for Ti) and bone (12-23 GPa) are still unsolved. 1) One way to alleviate the problems is, therefore, to reduce Young's modulus of pure Ti by introducing pores, thereby minimizing damages to tissues adjacent to the implant and eventually prolonging device life time.…”

Section: Introductionmentioning

confidence: 99%

Microstructures and Mechanical Properties of Porous Titanium Compacts Prepared by Powder Sintering

2002

View full text Add to dashboard Cite

Using pure Ti powder with particle sizes from 300 to 500 µm prepared by the plasma rotating electrode process (PREP), porous pure Ti compacts for biomedical applications were synthesized by powder sintering, and microstructures and mechanical properties of the compacts were investigated in this study. Porous compacts having porosity of 19-35 vol% are successfully fabricated by controlling sintering condition. It is found that Young's modulus and compressive yield strength decrease linearly with increasing porosity, and porous Ti compacts having porosity of about 30-35 vol% exhibit identical Young's modulus of human bone.

show abstract

Section: Introductionmentioning

confidence: 99%

Microstructures and Mechanical Properties of Porous Titanium Compacts Prepared by Powder Sintering

2002

View full text Add to dashboard Cite

show abstract

“…Implants manufactured by DLMS with characteristics of graded elasticity have also been shown to transfer stress from implants to the bone more naturally. 32 In this study, the MG63 cell line was cultured on DLMS and MAO implants. We found that cells on DLMS implants spread out more podia than those on MAO implants, and these abundant podia enabled the cells to tightly anchor themselves to the implant surfaces.…”

mentioning

confidence: 99%

The influence of direct laser metal sintering implants on the early stages of osseointegration in diabetic mini-pigs

Tan

Liu

Cai

et al. 2017

IJN

View full text Add to dashboard Cite

Background High failure rates of oral implants have been reported in diabetic patients due to the disruption of osseointegration. The aim of this study was to investigate whether direct laser metal sintering (DLMS) could improve osseointegration in diabetic animal models. Methods Surface characterizations were carried out on two types of implants. Cell morphology and the osteogenic-related gene expression of MG63 cells were observed under conditions of DLMS and microarc oxidation (MAO). A diabetes model in mini-pigs was established by intravenous injection of streptozotocin (150 mg/kg), and a total of 36 implants were inserted into the mandibular region. Micro-computed tomography (micro-CT) and histologic evaluations were performed 3 and 6 months after implantation. Results The Ra (the average of the absolute height of all points) of MAO surface was 2.3±0.3 µm while the DLMS surface showed the Ra of 27.4±1.1 µm. The cells on DLMS implants spread out more podia than those on MAO implants through cell morphology analysis. Osteogenic-related gene expression was also dramatically increased in the DLMS group. Obvious improvement was observed in the micro-CT and Van Gieson staining analyses of DLMS implants compared with MAO at 3 months, although this difference disappeared by 6 months. DLMS implants showed a higher bone–implant contact percentage (33.2%±11.2%) at 3 months compared with MAO group (18.9%±7.3%) while similar results were showed at 6 months between DLMS group (42.8%±10.1%) and MAO group (38.3%±10.8%). Conclusion The three-dimensional environment of implant surfaces with highly porous and fully interconnected channel and pore architectures can improve cell spreading and accelerate the progress of osseointegration in diabetic mini-pigs.

show abstract

“…En este campo han sido numerosos los estudios realizados [Nomura 2005, Wen 2001, Cirincione 2002, Asaoka 2003, Oh 2002, Kujala 2003, Thieme 2001, Li J.P. 2004], tratando tanto de recubrir el material sólido, como de crear un implante poroso en su totalidad.…”

Section: Métodos De Modificación De La Rigidez Empleados En Titaniounclassified

“…Por ello, mientras que métodos como la síntesis reactiva apenas han sido investigados, la viabilidad de otros procesos, como la técnica de HIP con gas atrapado [Degischer 2002], la sinterización de microesferas [Cirincione 2002, Thieme 2001, o el método de espaciadores [Bram 2005, Laptev 2004] si ha sido demostrada. Kupp 2002, Ryan 2006, Esen 2007.…”

Section: Métodos De Modificación De La Rigidez Empleados En Titaniounclassified

“…Tal es así, que al emplear moldes de gres y alúmina no se observaba una correlación directa con la temperatura y tiempo de sinterización, como cabria esperar [Thieme 2001, Oh 2003, Asaoka 2003]. Por el contrario, el recubrimiento del molde con itria minimiza la reactividad, evitando la absorción y combinación del titanio con elementos no deseados.…”

Titanium Powder Sintering for Preparation of a Porous FGM Destined as a Skeletal Replacement Implant

Cited by 71 publications

References 0 publications

Microstructures and Mechanical Properties of Porous Titanium Compacts Prepared by Powder Sintering

Microstructures and Mechanical Properties of Porous Titanium Compacts Prepared by Powder Sintering

The influence of direct laser metal sintering implants on the early stages of osseointegration in diabetic mini-pigs

Desarrollo de piezas porosas de Ti6Al4V mediante técnicas pulvimetalúrgicas

Contact Info

Product

Resources

About