Tithonia diversifolia pectin – reduced graphene oxide and its cytotoxic activity

Green synthesis of selenium nanoparticles capped by Tithonia diversifolia pectin for anti‐inflammation activity

“…11 Pectin from T. diversifolia, a significant polysaccharide, has been used as a capping agent in several green nanosystems with specific bioactivity. 12,13 In addition to the stabilizer role, T. diversifolia pectin also improved the biocompatibility and bioavailability of these systems.…”

“…Tithonia diversifolia , a plant in the family Asteraceae, has been known to contain several bioactive compounds such as alkaloids, saponins, flavonoids, sesquiterpene lactones, etc 11 . Pectin from T. diversifolia , a significant polysaccharide, has been used as a capping agent in several green nanosystems with specific bioactivity 12,13 . In addition to the stabilizer role, T. diversifolia pectin also improved the biocompatibility and bioavailability of these systems.…”

Reduced Graphene Oxide Incorporated Acellular Dermal Composite Scaffold Enables Efficient Local Delivery of Mesenchymal Stem Cells for Accelerating Diabetic Wound Healing

“…Graphene, a two-dimensional honeycomb lattice, attracts increasing research interests from all over the world owing to the admirable physicochemical properties . Hence biomaterials incorporated with graphene have exceptional electrical conductivity, stability, biomechanics, and biocompatibility. − Graphene-related nanomaterials have emerged in biomedical applications, such as drug transport, biosensing, bioimaging, and biological scaffolds, for multifarious regenerative medicines involving stem cell proliferation and differentiation. − However, the cytotoxicity of the pristine graphene and graphene oxide (GO) limits their application in biomedicine. , In fact, reduced graphene oxide (RGO)prepared by removing most oxygen-containing groups of graphene oxide (GO) with reducing conditionshas different physicochemical properties to decrease cellular uptake and reduce toxicity. , Recent studies have also shown that RGO at a certain concentration can induce angiogenesis by increasing intracellular reactive oxygen species concentration. , Therefore, RGO-related biomaterial scaffolds are beneficial for cell adhesion and proliferation due to excellent electroconductivity, lipophilicity, and biocompatibility. − Therefore, it is reasonable to fabricate the RGO-modified ADM composite scaffold with improved conductivity, mechanics, and biocompatibility for highly efficient stem cell transplantation and diabetic wound healing.…”