To Study Zinc Deficiency as a Risk Factor for Febrile Convulsions

Subbarao, Pinnaka; Apoorva, P; Kathiravan, K; Ramachandran, P. Veeraraghavan

doi:10.14260/jemds/2019/267

Cited by 3 publications

(2 citation statements)

References 21 publications

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“…According to a study, blood lead levels exceeding 10 g/dL can impair short-term memory, reduce intelligence quotient (IQ), and make it difficult to concentrate. In that study, patients' blood lead levels did not correlate with their age or fever (Subbarao et al, 2019).…”

Section: Manganesementioning

confidence: 69%

Role of Minerals in Childhood Epilepsy

Abdelbasir

Hassan²,

Mahmoud³

et al. 2023

SVU-International Journal of Medical Sciences

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Background: The cornerstone of brain activity is changes in membrane voltage caused by ion fluxes through voltage and transmitter-gated channels. Therefore, electrochemical gradients across the membrane determine the direction and driving force for ion flow, which in turn establishes synaptic transmission and signal propagation parameters.Numerous methods create ion concentration gradients and specialised transporter proteins are among them. However, ionic fluxes via channels can alter transmembrane gradients during times of increased brain activity, which is projected to have an impact on the characteristics of ongoing synaptic transmission. Both healthy and unhealthy brain processes involve activityinduced alterations to ion concentration gradients. Patients with epilepsy display a variety of altered trace elements, electrolytes, and free radical scavenging enzyme statuses. Minerals play an important role in regulating ion concentration gradients through their various biological actions. Objectives:This review would contribute in increasing understanding of the role of minerals in childhood epilepsy and the different mechanisms by which different types of minerals modulate seizures in children. Conclusion:The serum level of various trace elements and heavy metals influences the impact of epilepsy. In infantile epilepsy, high calcium concentrations in epileptic neurons remain elevated during both the acute damage and chronic epilepsy phases, and they play a role in the maintenance of spontaneous recurrent seizures.

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Section: Manganesementioning

confidence: 69%

Role of Minerals in Childhood Epilepsy

Abdelbasir

Hassan²,

Mahmoud³

et al. 2023

SVU-International Journal of Medical Sciences

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“…Thus, zinc deficiency is also associated with negative outcomes such as increased morbimortality at birth, increased severity of infectious diseases, stunted growth, and physiological alterations (anorexia, hypogonadism, hypogeusia (reduced sense of taste), dermatitis, dysfunctions of the immune system, and oxidative and neuropsychological damages) [109]. Zinc deficiency is also associated with diarrheic manifestations and predisposition to fever convulsions in children between 6 days and 6 months of age [110].…”

Section: Zincmentioning

confidence: 99%

Minerals in Pregnancy and Their Impact on Child Growth and Development

et al. 2020

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During pregnancy, women undergo metabolic and physiological changes, and their needs are higher, to maintain growth and development of the fetus. If the nutritional status of the expectant mother is not satisfactory, some maternal and neonatal complications can occur. In the second and third trimester of pregnancy, there is a reserve of nutrients in the fetus that can be utilized after birth; thereby, children present an accelerated growth in the first years of life, which is a proven response to the available nutrition pattern. However, if such a pattern is insufficient, there will be deficits during development, including brain function. Therefore, despite many recent published works about gestational nutrition, uncertainties still remain on the mechanisms of absorption, distribution, and excretion of micronutrients. Further elucidation is needed to better understand the impacts caused either by deficiency or excess of some micronutrients. Thus, to illustrate the contributions of minerals during prenatal development and in children, iodine, selenium, iron, zinc, calcium, and magnesium were selected. Our study sought to review the consequences related to gestational deficiency of the referred minerals and their impact on growth and development in children born from mothers with such deficiencies

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