To the Editor:

Sio, Ilario de; Castellano, L.; Girolamo, V. De; Santolo, S. Scotto di; Marone, A.; Blanco, C. Del Vecchio; Marone, G.

doi:10.1053/jhep.2001.27955

Cited by 33 publications

(1 citation statement)

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“…Peritoneal seeding, however, disables any curative retreatment. The incidence of NTS varies between 0 and 12.5% in different studies [17, 18, 22, 23]. The true incidence of NTS after LITT and RFA may be underestimated because of the short follow-up of studies or because clinicians may have overlooked this uncommon complication.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Viable Tumour Tissue Attached to Needle Applicators after Local Ablation of Liver Tumours

et al. 2009

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Aim: Local recurrence and needle track seeding are serious complications after local ablation for liver malignancies and potentially affect long-term survival. The aim of this study was to assess the incidence of viable tissue adherent to the needle applicators after ablation to gain insight into the possible mechanisms of local recurrence and needle track seeding. Methods: A total of 40 consecutive patients underwent 59 local liver ablations. Cells and tissue attached to the needle applicators were analysed for morphology (HE, PAP and Giemsa staining) and viability (G6PD staining). Results: Macroscopic tissue adherence was visible following 31 of the ablative procedures, all with radiofrequency ablation. Four applications were performed percutaneously and 27 during an open procedure. Morphologically intact tumour cells could be identified in 8 patients (20%), and viable tumour cells in 5 patients (12.5%). Morphologically intact tumour cells or viable tumour cells could only be demonstrated when track ablation was not performed. Conclusion: Viable tumour cells adherent to the needle applicators were found in an alarming 12.5% of patients after local ablation. We recommend track ablation not only after the procedure but also during any shifting and (re-)positioning to prevent shedding of viable tumour cells during or after ablation.

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Section: Introductionmentioning

confidence: 99%

Assessment of Viable Tumour Tissue Attached to Needle Applicators after Local Ablation of Liver Tumours

et al. 2009

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Risk factors for local recurrence of small hepatocellular carcinoma tumors after a single session, single application of percutaneous radiofrequency ablation

Komorizono

Oketani

Sako³

et al. 2003

Cancer

306

190

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This work is aimed to provide a systematic design procedure to determine the process configuration, the relative position of the reactive zone, and separation sections. Instead of investigating real chemical systems, ideal chemical reaction systems with different relative volatility rankings will be studied. This provides a gradual transition as the reaction and separation properties change. The reaction considered is a reversible reaction, A + B ⇔︁ C + D, and this constitutes a quaternary system with 24 (4) possible relative volatility arrangements. These 24 systems can further be grouped into six categories according to the ranking of relative volatilities of reactants and products. The likely process configurations will be explored and design will be optimized based on the total annual cost (TAC). The results clearly indicate that the relative volatility rankings play a dominant role in the reactive distillation configuration and the TAC varies by a factor of ∼7 as we move from the most favorable case (reactants are intermediate keys) to the least favorable relative volatility ranking (products are intermediate keys). Finally, heuristics are given to correlate the relative volatility ranking to the TAC. © 2007 American Institute of Chemical Engineers AIChE J, 2007

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Differences and similarities in the approach to hepatocellular carcinoma between Eastern and Western institutions

2004

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To the Editor:

Cited by 33 publications

References 0 publications

Assessment of Viable Tumour Tissue Attached to Needle Applicators after Local Ablation of Liver Tumours

Assessment of Viable Tumour Tissue Attached to Needle Applicators after Local Ablation of Liver Tumours

Risk factors for local recurrence of small hepatocellular carcinoma tumors after a single session, single application of percutaneous radiofrequency ablation

Differences and similarities in the approach to hepatocellular carcinoma between Eastern and Western institutions

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