Tobacco Use and Skin Disease

Smoker’s Mustache Revisited: Upper Lip Hair Yellow Discoloration Associated With Tobacco

“…Nicotine sign refers to the yellow discoloration resulting from continued staining of the nails with tobacco by-products [ 6 ]. Harlequin nail is a distinct physical sign that was described in 1990 by Verghese et al since they considered the affected fingernails to be fancifully varied in color; it presents as a sharp line of demarcation between the distal tobacco by-products-stained nail and proximal growth of the normal nail [ 7 ].…”

“…Fingernails grow approximately 3 millimeters per month. The harlequin nail enables the clinician to calculate when a patient has abruptly stopped smoking, often due to a severe illness such as a stroke [ 6 - 8 ]. Our patient, a 54-year-old Asian man, had approximately 3 millimeters of normal-appearing nail distal to the proximal nail fold; assuming at least 1 millimeter of normal nail beneath his proximal nail fold, this would total 4 millimeters and corresponds to his smoking cessation about one and a half months earlier.…”

Surgical treatment of patients with oral leukoplakia

“…[28,61,62]. Сочетанное воздействие термических и химических раздражителей на СОР (аммиачные и феноловые соеди-нения, никотин, производные дегтя) наблюдается при ку-рении [27,28,70,72,75,77,95,99,105,109].…”