BACKGROUND
The advent of online task-distribution has opened a new avenue to efficiently gather community perspectives needed for utility estimation. Methodological consensus for estimating pediatric utilities is lacking, with disagreement over whom to sample, what perspective (patient vs. parent), and whether instrument-induced anchoring bias is significant. We sought to determine what methodological factors potentially impact utility estimates for vesicoureteral reflux (VUR).
DESIGN
Cross-sectional surveys using a time-trade-off (TTO) instrument were conducted via Amazon's Mechanical Turk online interface; respondents were randomized to answer questions from child, parent, or dyad perspectives on the utility of a VUR health state and one of three “warm-up” scenarios (paralysis, common cold, none) prior to a VUR scenario. Utility estimates and potential predictors were fitted to a generalized linear model to determine what factors most impacted utilities.
RESULTS
A total of 1,627 responses were obtained. Mean respondent age was 34.9 years; 48% were female; 38% were married; and 44% had children. Utility values were uninfluenced by child/personal VUR/UTI history, income, or race. Utilities were affected by perspective, and were higher in the child group (34% lower in parent v. child, p<0.001; 13% lower in dyad v. child, p<0.001). VUR utility was not significantly affected by the presence or type of TTO warm-up scenario (p=0.17).
CONCLUSIONS
TTO perspective affects utilities when estimated via an online interface, however, utilities are unaffected by the presence, type, or absence of warm-up scenarios. These findings could have significant methodological implications for future utility elicitations in other pediatric conditions.