Topical application of Garcinia mangostana L. pericarp gel as an adjunct to periodontal treatment

Rassameemasmaung, Supanee; Sirikulsathean, Anongporn; Amornchat, Cholticha; Maungmingsook, Pawinee; Rojanapanthu, Pleumchitt; Gritsanaphan, Wandee

doi:10.1016/j.ctim.2007.12.004

Cited by 26 publications

(39 citation statements)

References 20 publications

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“…This was in accordance with Rassameemasmaung et al. 's study, which also showed a greater reduction in pocket depth with the application of MGA gel as a LDD . Tissue shrinkage usually occurs after SRP, which could lead to the reduction of PPD.…”

Section: Discussionsupporting

confidence: 90%

Clinical and microbiological efficacy of 4% Garcinia mangostana L. pericarp gel as local drug delivery in the treatment of chronic periodontitis: A randomized, controlled clinical trial

Mahendra

Svedha

et al. 2017

J of Invest & Clin Dent

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Section: Discussionsupporting

confidence: 90%

Clinical and microbiological efficacy of 4% Garcinia mangostana L. pericarp gel as local drug delivery in the treatment of chronic periodontitis: A randomized, controlled clinical trial

Mahendra

Svedha

et al. 2017

J of Invest & Clin Dent

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“…Topical application of a gel containing extract of mangosteen pericarp decreased periodontal inflammation suggesting that the formulation may be useful as an adjuvant. However, the xanthone content and composition in the gel was not reported for this study [39]. Ingestion of a blended mangosteen juice decreased serum C-reactive protein (CRP) levels.…”

Section: Anti-inflammatory Activity Of Xanthonesmentioning

confidence: 89%

Biological Activities and Bioavailability of Mangosteen Xanthones: A Critical Review of the Current Evidence

2013

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Mangosteen (Garcinia mangostana L.) is a tropical tree native to Southeast Asia that produces a fruit whose pericarp contains a family of tricyclic isoprenylated polyphenols referred to as xanthones. Numerous in vitro studies have shown that these xanthones possess anti-oxidant, anti-proliferative, pro-apoptotic, anti-inflammatory and anti-carcinogenic activities. Aggressive marketing of such health promoting benefits has resulted in mangosteen’s classification as a “superfruit”. This has led to sales of mangosteen containing beverages in USA alone exceeding $200 million in 2008 despite very limited animal and human studies. This review will (a) critically address recent reports of in vivo studies on the bioavailability and metabolism of mangosteen xanthones, (b) update the in vitro and in vivo data on anti-cancer and anti-inflammatory activities of mangosteen xanthones, and (c) suggest needed areas of inquiry regarding the absorption, metabolism and efficacy of mangosteen xanthones.

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“…Some studies suggested that mouthwash containing mangosteen pericarp has benefits as an adjunct to periodontal treatment and for control of oral malodor. [1415]…”

Section: Discussionmentioning

confidence: 99%

Comparative clinical efficacy of three toothpastes in the control of supragingival calculus formation

Kraivaphan

Amornchat

2017

Eur J Dent

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Objectives:The purpose of this double-blind, parallel clinical study was to assess clinical efficacy in supragingival calculus formation reduction using Abhaibhubejhr Herbal Toothpaste compared to Colgate Total and Colgate Cavity Protection toothpastes.Materials and Methods:A total of 150 subjects participated in the pretest phase. All subjects were given oral soft/hard tissue evaluation, calculus examination using Volpe-Manhold calculus, and whole mouth oral prophylaxis. They received noncalculus control fluoride toothpaste and a soft-bristled toothbrush to brush for 1 min two times daily for 8 weeks. After which, subjects were given a test phase oral soft/hard tissue evaluation and calculus examination and were randomized into one of the three toothpaste groups. All subjects in the test phase received a whole mouth oral prophylaxis and were given their assigned toothpaste and a soft-bristled toothbrush to brush for 1 min two times a day for 12 weeks. Thereafter, subjects were assessed for their oral soft/hard tissue and calculus formation.Results:Mean Volpe-Manhold calculus index scores for the Cavity Protection, Abhaibhubejhr, and Total toothpaste groups were 0.78, 0.62, and 0.48, respectively, at the 12-week test phase evaluation. Abhaibhubejhr and Total toothpaste groups show 20.51% and 38.46% significantly less calculus formation than the Cavity Protection toothpaste group (P < 0.05). Total toothpaste group also show 22.58% significantly less calculus formation than the Abhaibhubejhr toothpaste group (P < 0.05).Conclusion:The use of Colgate Total toothpaste over a 12-week period was clinically more effective than either Abhaibhubejhr or Colgate Cavity Protection toothpastes in controlling supragingival calculus formation.

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Topical application of Garcinia mangostana L. pericarp gel as an adjunct to periodontal treatment

Cited by 26 publications

References 20 publications

Clinical and microbiological efficacy of 4% Garcinia mangostana L. pericarp gel as local drug delivery in the treatment of chronic periodontitis: A randomized, controlled clinical trial

Clinical and microbiological efficacy of 4% Garcinia mangostana L. pericarp gel as local drug delivery in the treatment of chronic periodontitis: A randomized, controlled clinical trial

Biological Activities and Bioavailability of Mangosteen Xanthones: A Critical Review of the Current Evidence

Comparative clinical efficacy of three toothpastes in the control of supragingival calculus formation

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