Topical photodynamic therapy with 5-aminolevulinic acid for cervical high-risk HPV infection

Fu, Yu; Bao, Yingqiu; Hui, Ying; Gao, Xiaoman; Yang, Min; Chang, Jian-Min

doi:10.1016/j.pdpdt.2015.12.004

Cited by 41 publications

(18 citation statements)

References 15 publications

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“…[20–22] Among the 168 records identified from the Medline, EMBASE, Cochrane Central Register, and CPCI databases, 136 studies were screened after elimination of duplicate articles, and 70 full-text articles were retrieved after screening the title and abstract. After exclusion of 47 articles that were not relevant, 21 qualitative studies and 4 RCTs [23–26] were identified as meeting all the inclusion criteria (Supplementary S4).…”

Section: Resultsmentioning

confidence: 99%

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Efficacy and safety of photodynamic therapy for cervical intraepithelial neoplasia and human papilloma virus infection

Zhang

Sun

et al. 2018

Medicine

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Section: Resultsmentioning

confidence: 99%

“…1). Moreover, the risks of bias for randomization and allocation in three RCTS [24–26] are unclear. The 2015 study by Hillemanns et al [25] represents the largest study with a weight of 48.1% in the meta-analysis of CRR in CIN patients.…”

Section: Resultsmentioning

confidence: 99%

Efficacy and safety of photodynamic therapy for cervical intraepithelial neoplasia and human papilloma virus infection

Zhang

Sun

et al. 2018

Medicine

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“…PDT is another approach used widely to treat various cancers. Topical administration of PDT is considered to be most appropriate for cervical and vulval intraepithelial lesions ( 259 ). 5-Aminolevulinic acid (ALA)-mediated PDT to treat HPV-associated cervical condyloma has been evaluated for HPV-6, 11, 16, and 18.…”

Section: Therapeutic Approaches To Hpv-induced Diseasementioning

confidence: 99%

“…This indicates the efficacy and safety of the PDT ( 260 ). Topical ALA-PDT has been found efficacious and well tolerated when used to treat high-risk HPV infections ( 259 ). A photosensitizer dye IR700 coupled with HPV VLPs, when exposed to cervical cancer cell lines and 690-nm light causes necrosis-like cell death by inducing the influx of CD8+ and CD4+ T-cells into the treated tumors ( 261 ).…”

Section: Therapeutic Approaches To Hpv-induced Diseasementioning

confidence: 99%

Advances in Designing and Developing Vaccines, Drugs and Therapeutic Approaches to Counter Human Papilloma Virus

Dadar

Chakraborty²,

Dhama

et al. 2018

Front. Immunol.

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Human papillomavirus (HPV) is a viral infection with skin-to-skin based transmission mode. HPV annually caused over 500,000 cancer cases including cervical, anogenital and oropharyngeal cancer among others. HPV vaccination has become a public-health concern, worldwide, to prevent the cases of HPV infections including precancerous lesions, cervical cancers, and genital warts especially in adolescent female and male population by launching national programs with international alliances. Currently, available prophylactic and therapeutic vaccines are expensive to be used in developing countries for vaccination programs. The recent progress in immunotherapy, biotechnology, recombinant DNA technology and molecular biology along with alternative and complementary medicinal systems have paved novel ways and valuable opportunities to design and develop effective prophylactic and therapeutic vaccines, drugs and treatment approach to counter HPV effectively. Exploration and more researches on such advances could result in the gradual reduction in the incidences of HPV cases across the world. The present review presents a current global scenario and futuristic prospects of the advanced prophylactic and therapeutic approaches against HPV along with recent patents coverage of the progress and advances in drugs, vaccines and therapeutic regimens to effectively combat HPV infections and its cancerous conditions.

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“…The treatment group 39 patients received three treatments of ALA-PDT at two-week intervals. Research results have shown that PDT is an effective, safe and well-tolerated treatment for cervical HR-HPV infection (159). Fan et al in 2018 they conducted a study in which they used ALA-PDT for rosacea in Chinese patients.…”

Section: Fluorescence Diagnostics and Photodynamic Therapy In Cancer 533mentioning

confidence: 99%

Fluorescence Diagnostics and Photodynamic Therapy In Cancer

Ożóg¹,

Domka²,

Bartusik‐Aebisher³

et al. 2020

Acta Poloniae Pharmaceutica - Drug Research

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Recently, fluorescence diagnostics and photodynamic therapy (PDT) is increasingly gaining in popularity for clinical use. The purpose of this review was to describe the results of using laser and molecular techniques to develop targeted cancer therapy for improved drug delivery to cancer cells with regards to tissue visualization, single-cell localization, monitoring of treatment, and drug efficacy.

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Topical photodynamic therapy with 5-aminolevulinic acid for cervical high-risk HPV infection

Cited by 41 publications

References 15 publications

Efficacy and safety of photodynamic therapy for cervical intraepithelial neoplasia and human papilloma virus infection

Efficacy and safety of photodynamic therapy for cervical intraepithelial neoplasia and human papilloma virus infection

Advances in Designing and Developing Vaccines, Drugs and Therapeutic Approaches to Counter Human Papilloma Virus

Fluorescence Diagnostics and Photodynamic Therapy In Cancer

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