Topical treatment for facial burns

Hoogewerf, Cornelis J; Hop, M.J.; Nieuwenhuis, M.K.; Oen, I.M.M.H.; Middelkoop, Esther; Baar, Margriet E. van

doi:10.1002/14651858.cd008058.pub3

Cited by 16 publications

(18 citation statements)

References 72 publications

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“…Essential oils (EOs) derived from plants have recently been paid the greatest attention in a variety of practical disciplines such as food packaging, pharmaceutical, and cosmetic purposes [14,15]. This is due to not only they are 100% renewable materials, but they can be used as a promising agent for antimicrobial, anticancer therapy [16], as well as burn healing treatment [17,18]. Among of these EOs, cinnamon essential oil (CIEO) extracted from bark parts of Ceylon cinnamon (Cinnamomum cassia) has emerged promising impacts against pathogenic microbes and cancer cell diseases [19,20].…”

Section: Introductionmentioning

confidence: 99%

Development of antibacterial carboxymethyl cellulose/quaternized starch bionanocomposites based on cinnamon essential oil nanoemulsion for wound healing applications

Moustafa

Nasr

Youssef

2022

Biomass Conv. Bioref.

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Infectious diseases of skin wound–based bacteria are a considerable issue that often hinders the wound closure, thereby delaying the healing process. The use of wound dressing based-renewable polymers with natural essential oil could overcome the deficiencies of skin wounds. In this work, wound dressings from carboxymethyl cellulose (CMC)/quaternized starch (MS-Q188) in presence antimicrobial cinnamon essential oil (CIEO) nanoemulsion were prepared. Three variable ratios of CIEO (i.e., 1, 3, and 5 wt.%) in nanoemulsion forms were used to fabricate CMC/MS-Q188 bionanocomposites. The resulting bionanocomposites were investigated by XRD, FT-IR, and SEM. The mechanical, hydrophilicity, and barrier properties were evaluated, the outcomes of which demonstrated the tensile properties were achieved. However, the hydrophilicity, water vapor, and oxygen barrier properties were affected when the CIEO nanoemulsion added to the matrix. The migration of polymer components to the skin tissue and cytotoxic effect were investigated by cytotoxicity assays. The outcomes showed that the cell viability was located in the range of ~ 92–100% even at all studied concentrations, indicating there was no cytotoxicity to the cells. The inhibitory effects of CIEO nanoemulsion ratios on different pathogenic microbes were also verified. The developed bionanocomposites open opportunities for their use in smart skin wound dressings and biomedical applications.

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Section: Introductionmentioning

confidence: 99%

Development of antibacterial carboxymethyl cellulose/quaternized starch bionanocomposites based on cinnamon essential oil nanoemulsion for wound healing applications

Moustafa

Nasr

Youssef

2022

Biomass Conv. Bioref.

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“…The clinical outcome of wound recovery is primarily determined by the time to complete wound healing, or the proportion of wounds that fully healed (epithelialization) within a specific period of time and wound infection [ 172 ]. Hydrogel wound dressings have many benefits for wound repair.…”

Section: Biomaterials For Preparing Hydrogelsmentioning

confidence: 99%

Hydrogel Preparation Methods and Biomaterials for Wound Dressing

Liang

et al. 2021

Life

154

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Wounds have become one of the causes of death worldwide. The metabolic disorder of the wound microenvironment can lead to a series of serious symptoms, especially chronic wounds that bring great pain to patients, and there is currently no effective and widely used wound dressing. Therefore, it is important to develop new multifunctional wound dressings. Hydrogel is an ideal dressing candidate because of its 3D structure, good permeability, excellent biocompatibility, and ability to provide a moist environment for wound repair, which overcomes the shortcomings of traditional dressings. This article first briefly introduces the skin wound healing process, then the preparation methods of hydrogel dressings and the characteristics of hydrogel wound dressings made of natural biomaterials and synthetic materials are introduced. Finally, the development prospects and challenges of hydrogel wound dressings are discussed.

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“…Wounds located in oral and maxillofacial regions also cause hypertrophy or scar, leading to dysfunction of facial muscle and adverse effect to aesthetics. Scars may cause itching discomfort or even neuropathic pain which reduces the life quality of patients 96 .…”

Section: Trwound Healingmentioning

confidence: 99%