Total antioxidant power in sled dogs supplemented with blueberries and the comparison of blood parameters associated with exercise

Dunlap, Kriya L.; Reynolds, Arleigh J.; Duffy, Lawrence K.

doi:10.1016/j.cbpa.2005.09.007

Cited by 61 publications

(49 citation statements)

References 30 publications

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“…When compared to Greyhounds and agility dogs who show a 3-to 10-fold higher serum lactate concentration after an exercise bout, our study dogs showed little muscle glycolytic activity after 2 hours of low intensity exercise [12] [34]. This suggests that the dogs were running primarily from energy generated from the beta-oxidation of fatty acids, which would be expected for dogs running between 30% -50% of their maximal oxygen capacity [20] [35]. However, even at this low intensity of exercise, our study dogs appeared to be alkalotic, similar to field trial Labradors who showed a pronounced respiratory alkalosis following exercise [36].…”

Section: Discussionmentioning

confidence: 73%

“…Exercise consisted of all dogs running simultaneously on an exercise wheel as is typical for conditioning canine athletes (sled dogs and hunting dogs) at 11 km/hour for 120 minutes on two consecutive days between 7 and 9 am. This exercise regimen simulates a low intensity endurance exercise equivalent to approximately 30% -40% of their maximal oxygen consumption [20]. At each half hour interval of exercise, the direction in which the dogs ran was changed.…”

Section: Dog Exercise Sessionsmentioning

confidence: 99%

“…Elevated serum uric acid during both short and long duration strenuous activities is associated with decreased exercise-induced oxidative damage [20]- [22]. In addition, supplementation of humans with uric acid prevented exercise-induced elevation of 8-isoPs [23].…”

Section: Introductionmentioning

confidence: 95%

“…Uric acid, a potent antioxidant, is suggested to prevent elevations in oxidative damage [14] [20]. Elevated serum uric acid during both short and long duration strenuous activities is associated with decreased exercise-induced oxidative damage [20]- [22].…”

Section: Introductionmentioning

confidence: 99%

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The Effects of Low Intensity Endurance Activity on Various Physiological Parameters and Exercise Induced Oxidative Stress in Dogs

Huntingford¹,

Levine²,

Mustacich³

et al. 2014

OJVM

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The study of canine athlete physiology has focused on endurance sled dog racing and high intensity short duration Greyhound racing, yet the number of dogs competing in low intensity endurance activities is rising due to the increased numbers of hunting and companion dog activities. There is little information on the physiological effect of longer duration low intensity endurance activities. We set out to evaluate the serum biochemistry, oxidative stress, and cortisol response before and after two consecutive days of exercise in ten healthy unconditioned male dogs. Exercise sessions consisted of 120 minutes on an exercise wheel at 11 km/hour on 2 consecutive days. Blood was collected at four time points: 24 hours pre-exercise (sample 1, Day 0, resting); 2 min post-exercise on days 1 and 2, (samples 2 and 3, respectively); and 20 hours post-exercise, collected on day 3(sample 4). Hematocrit, blood gases, serum chemistry, uric acid, cortisol, and F2-isoprostanes were determined. Serum biochemistry and hematocrit suggested hemoconcentration, mild muscle damage and respiratory alkalosis during exercise, which was expected in the unconditioned canine athlete. In addition, plasma indices of oxidative damage (F2-isoprostanes) increased, as did plasma uric acid (an endogenous antioxidant). Importantly, similar to human studies, plasma F2-isoprostanes decreased 24 hours after exercise suggesting a protective effect of exercise. Serum cortisol concentrations were also markedly elevated at the end of exercise on both days suggesting that timing of sampling may play a role in interpreting cortisol results when looking at previous field studies.

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Section: Discussionmentioning

confidence: 73%

Section: Dog Exercise Sessionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Effects of Low Intensity Endurance Activity on Various Physiological Parameters and Exercise Induced Oxidative Stress in Dogs

Huntingford¹,

Levine²,

Mustacich³

et al. 2014

OJVM

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“…Parallel to the studies on the benefi cial effects of exercise and its effects on oxidative stress investigations on the effects of dietary supplementation with antioxidants have been carried out by a number of authors. In the recent years special attention has been focused on the effects of ingested free radical scavenging polyphenols present in grapes [11,12], rose-hips [13,14], blueberries [15,16], and pomegranates [17][18][19] on oxidative stress markers in animals and humans. The major bioactive compounds within these fruits are besides polyphenols, ascorbic acid, tocopherol, lycopene, tannins, ß carotene, sugars, amino acids, and essential fatty acids [20].…”

Section: Introductionmentioning

confidence: 99%

Effects Of Rose-Hip And Grapeseed Dietary Supplementation On Serum Oxidative Stress Parameters In Dogs Before And After Physical Exercise

Kukovska¹,

Celeska

Ruskovska

et al. 2015

Acta Veterinaria

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The aim of this study was to evaluate the effects of 60 days of rose-hip and grapeseed dietary supplementation of a balanced home-cooked diet on serum oxidative stress parameters: ROMs, MDA and FRAP in army service dogs before and after regular physical exercise. The dogs were fed a balanced cooked diet as instructed by army standards until the initial blood sampling in June. Thereon the dogs were randomly allotted to 4 groups according to the dietary regime: dogs maintained on a balanced cooked diet according to army standards, branded dry dog food, cooked diet with added 500 mg rose-hip extract, and cooked diet with added 100 mg grapeseed extract for a 60 day period from June to September after which all 4 groups were fed the standard cooked meal diet. Sampling was performed at the beginning of the experiment (June), 60 days from the start of the treatment (September) and finally 60 days after the end of supplementation (November). Statistical analysis of the results included descriptive statistical parameters: mean (M), standard deviation (SD), and variation coefficient (CV%). In order to test the statistical significance of the differences between treatments a multifactor variance test (ANOVA) was performed for ROM, MDA and FRAP and the combined effects of diet, exercise and time period were observed. The initial (in June) increase in MDA and ROMs after exercise indicates the presence of oxidative stress 30 minutes after exercise. However, the antioxidative effects of rose-hip and grapeseed extracts are not conclusive, as multifactor ANOVA testing of time, diet, and exercise factors did not reveal for MDA statistically significant differences either at 60 days of supplementation nor 60 days after withdrawal of the supplements. Only one distinct exception was recorded for the prolonged antioxidative effects reflected in significantly decreased (p<0.01) ROMs before and after exercise in dogs fed the branded dry food 60 days after the end of such dietary regime (November). FRAP values tend to be higher (p>0.05) after exercise compared to before exercise in all experimental groups in November, indicating on a possible redistribution and upregulation of endogenous antioxidants during the experiment.

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The Role of Nutrition in Canine Performance and Rehabilitation

Wakshlag

2013

Canine Sports Medicine and Rehabilitation

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Total antioxidant power in sled dogs supplemented with blueberries and the comparison of blood parameters associated with exercise

Cited by 61 publications

References 30 publications

The Effects of Low Intensity Endurance Activity on Various Physiological Parameters and Exercise Induced Oxidative Stress in Dogs

The Effects of Low Intensity Endurance Activity on Various Physiological Parameters and Exercise Induced Oxidative Stress in Dogs

Effects Of Rose-Hip And Grapeseed Dietary Supplementation On Serum Oxidative Stress Parameters In Dogs Before And After Physical Exercise

The Role of Nutrition in Canine Performance and Rehabilitation

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