Total Diagnostic Delay in Oral Cancer may be Related to Advanced Disease Stage at Diagnosis

Cleveland, Jennifer L.; Thornton-Evans, Gina

doi:10.1016/j.jebdp.2012.03.018

Cited by 9 publications

(6 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most cancer research communities continue to agree that early detection is important for providing appropriate treatment to reduce disease burdens and mortality rates. [ 48 , 49 ] In this study, we did not raise awareness of “delay” in terms of this term's linguistic definition or categorization, both of which have been inconsistent across numerous studies. We instead determined the average interval between initial diagnosis and treatment among patients with oral cancer.…”

Section: Discussionmentioning

confidence: 77%

Assessment of duration until initial treatment and its determining factors among newly diagnosed oral cancer patients

2016

View full text Add to dashboard Cite

Few studies have focused on the early treatment stages of cancer, and the impact of treatment delay on oncologic outcomes is poorly defined. We used oral cancer as an example to investigate the distribution of durations until initial treatment.This study was conducted using the National Health Insurance Research Database, which is linked to Taiwan's Cancer Registry and Death Registry databases. We defined “cutoff points for first-time treatment” according to a weekly schedule and sorted the patients into 2 groups based on whether their duration until initial treatment was longer or shorter than each cutoff. We then calculated the Kaplan–Meier estimator to determine the difference in survival rates between the 2 groups and performed logistic regression to identify determining factors.The average time between diagnosis and initial treatment was approximately 22.45 days. The average survival duration was 1363 days (standard deviation: 473.06 days). Oral cancer patients had no statistically significant differences in survival until a cutoff point of 3 weeks was used (with survival duration 71 days longer if initial treatment was received within 3 weeks). Patients with higher incomes or higher Charlson comorbidity index scores and patients treated at a hospital in a region with medium urbanization had lower likelihoods of treatment delay, whereas older patients were at higher risk of treatment delay.The attitudes, beliefs, and social contexts of oral cancer patients influence the treatment-seeking behaviors of these patients. Therefore, the government should advocate the merits of the referral system for cancer treatment or improve quality assurance for cancer diagnoses across different types of hospitals. Health authorities should also educate patients or use a case manager to encourage prompt treatment within 3 weeks and should provide screening and prevention services, particularly for high-risk groups, to reduce mortality risk.

show abstract

Section: Discussionmentioning

confidence: 77%

Assessment of duration until initial treatment and its determining factors among newly diagnosed oral cancer patients

2016

View full text Add to dashboard Cite

show abstract

“…Disease stage is also considered an outcome of interest for research under this topic as it correlates well with patient survival . A meta‐analytical study has reported total diagnostic delay in oral and oropharyngeal cancer may be related to advanced stage at diagnosis . but some of the case series in this study included oropharyngeal locations as well as other nonoral sites .…”

Section: Discussionmentioning

confidence: 99%

Early oral cancer diagnosis: The Aarhus statement perspective. A systematic review and meta‐analysis

et al. 2015

View full text Add to dashboard Cite

show abstract

“…11 Currently, more than 60% of patients with HNC present and receive a diagnosis of advanced-stage (III or IV) lesions with a mean 5-year survival rate of 50%. 11,12 This is in contrast to pa-tients with a diagnosis of early-stage disease, for whom the 5-year survival rate is in excess of 80%. 12 Our current data mirror this trend, with more than 80% of our patients presenting at an advanced stage.…”

Section: Discussionmentioning

confidence: 99%

Initial Experience of a Patient Navigation Model for Head and Neck Cancer

Ohlstein

Brody-Camp

Friedman

et al. 2015

JAMA Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

Total Diagnostic Delay in Oral Cancer may be Related to Advanced Disease Stage at Diagnosis

Cited by 9 publications

References 9 publications

Assessment of duration until initial treatment and its determining factors among newly diagnosed oral cancer patients

Assessment of duration until initial treatment and its determining factors among newly diagnosed oral cancer patients

Early oral cancer diagnosis: The Aarhus statement perspective. A systematic review and meta‐analysis

Initial Experience of a Patient Navigation Model for Head and Neck Cancer

Contact Info

Product

Resources

About