Total intravenous anesthesia without muscle relaxant in a patient with amyotrophic lateral sclerosis

Lee, Dong Chul; Lee, Kyung Cheon; Kim, Ji Young; Park, Yeon Soo; Chang, Young Jin

doi:10.1007/s00540-008-0655-x

Cited by 22 publications

(16 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Total intravenous induction of anesthesia with propofol and remifentanil without NMBAs has been successfully performed in a woman with amyotrophic lateral sclerosis [90] and children with Duchenne's muscular dystrophy [91,92]. Total intravenous induction of anesthesia with propofol and remifentanil without NMBAs has been successfully performed in a woman with amyotrophic lateral sclerosis [90] and children with Duchenne's muscular dystrophy [91,92].…”

Section: N E U R O M U S C U L a R D I S E A S E Smentioning

confidence: 99%

Management of the airway without the use of neuromuscular blocking agents: the use of remifentanil

Fotopoulou

Theocharis

Vasileiou

et al. 2011

Fundamemntal Clinical Pharma

View full text Add to dashboard Cite

Remifentanil belongs to opioid drugs, and its pharmacokinetic characteristics make it unique in this class of drugs and appropriate for use during intubation without neuromuscular blockage. This up-to-date review aims to summarize the findings of recent studies regarding remifentanil and intubation. Remifentanil combined either with propofol or with inhaled anesthetic agents has been proved to provide acceptable intubating conditions. Regarding children patients, remifentanil can be used safely, and as far as intubating conditions are concerned, its effectiveness is as excellent as with neuromuscular blockage. Strong evidence exists that illuminates the usefulness of the drug in cases of difficult airway as well as in neuromuscular diseases. Beyond all these favorable characteristics, anesthesiologists must be conscious with the use of remifentanil.

show abstract

Section: N E U R O M U S C U L a R D I S E A S E Smentioning

confidence: 99%

Management of the airway without the use of neuromuscular blocking agents: the use of remifentanil

Fotopoulou

Theocharis

Vasileiou

et al. 2011

Fundamemntal Clinical Pharma

View full text Add to dashboard Cite

show abstract

“…These concerns are alleviated by abundant reports of anesthesia in a variety of surgeries in ALS patients, without evidence of decline. Surgeries have included feeding tube placement, diaphragmatic pacemaker implantation, spinal stem cell transplantation, and various other procedures 18,19,20,21 .…”

Section: Discussionmentioning

confidence: 99%

Physician perceptions about living organ donation in patients with Amyotrophic Lateral Sclerosis

Ansari

Bromberg

Gibson

2017

Clinical Neurology and Neurosurgery

View full text Add to dashboard Cite

Objectives Patients with Amyotrophic Lateral Sclerosis (ALS) have expressed desire to become living organ donors but are unable to do so with current organ donation policies. Our objective is to assess ALS patient's interest in organ donation, and perceived concerns of this practice by ALS neurologists. Patients and Methods An electronic survey was administered to ALS neurologists across the United States regarding living organ donation in ALS patients prior to respiratory failure. Results 52 complete responses were received from 121 invites. 67% (35/52) of neurologists expressed no concerns about living organ donation in ALS patients, and 33% had concerns. The concerns related to respiratory failure, anesthesia exposure and renal dysfunction. With their concerns addressed, 71% of neurologists reported that they would endorse living organ donation. 49% of neurologists reported being asked by a patient for information regarding living organ donation. ALS neurologists felt that 22.8% of ALS patients (median 19%) would be interested in learning more about organ donation, while only 6% of neurologists broach this subject with their patients. Conclusion Our results indicate that 1 in every 4 ALS patients may be interested in exploring options for living organ donation, and this topic is not routinely addressed by ALS clinics. These results indicate an unexplored area of patient interest. To honor a patient's wishes to donate, the transplant community will have to accommodate living organ donation from terminally ill patients, and address neurologist concerns. Such a practice could benefit two groups of patients.

show abstract

“…General anesthesia may cause aspiration and/or ventilatory depression, due to abnormal responses to muscle relaxants [4]. In general anesthesia, dose of nondepolarizing muscle relaxant should be reduced [5] or avoided [6] because of the possible occurrence of ventilatory depression because of abnormal responses to muscle relaxants. Therefore, regional anesthesia can be considered a safer modality than that of general anesthesia, on the respiration system, in low extremity or abdominal operation.…”

Section: Discussionmentioning

confidence: 99%

Spinal anesthetic management for discectomy in a patient with amyotrophic lateral sclerosis -A case report-

Park

Son

Hwang

et al. 2012

Korean J Anesthesiol

View full text Add to dashboard Cite

Amyotrophic lateral sclerosis (ALS), also referred to as Lou Gehrig's disease, is a degenerative disorder of motor neuron system of the spinal cord and the cortical neuron. Patients with ALS present a unique challenge to the anesthesiologist. Respiratory muscle weakness, for instance, can result in trouble with proper breathing after general anesthesia. We report a case of spinal anesthesia for discectomy in a patient with ALS.

show abstract

Total intravenous anesthesia without muscle relaxant in a patient with amyotrophic lateral sclerosis

Cited by 22 publications

References 11 publications

Management of the airway without the use of neuromuscular blocking agents: the use of remifentanil

Management of the airway without the use of neuromuscular blocking agents: the use of remifentanil

Physician perceptions about living organ donation in patients with Amyotrophic Lateral Sclerosis

Spinal anesthetic management for discectomy in a patient with amyotrophic lateral sclerosis -A case report-

Contact Info

Product

Resources

About