Total microcystins analysis in water using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry

A sensitive method for the determination of total microcystins in water and sediment samples by liquid chromatography with fluorescence detection

“…19 Roy-Lachapelle et al detected MMPB with LDTD-APCI-MS/MS and the quantication limit was 0.2 mg L À1 . 7 Thus, the sensitivity of the proposed method was comparable with published methods based on mass spectrometry. Due to the low test cost and high sensitivity, this method may be a good option for the routine detection of MCs.…”

“…6 Moreover, it is doubtful that the PPIA and ELISA are equally sensitive to different MC variants. 7 Although these methods are generally effective for measuring the dissolved toxins in water, their application to analysis of MCs in other matrices (algae, sediment and tissue) requires prior solvent extraction, which may signicantly underestimate the total toxin content. 8 Meissner et al found that a considerable portion of MCs binds to protein in algae and is neglected by current analysis techniques based on solvent extraction.…”

A review of solar and visible light active TiO2 photocatalysis for treating bacteria, cyanotoxins and contaminants of emerging concern

“…Microcystins are stable, water-soluble molecules and are rapidly absorbed by the liver resulting in harmful results such as cell necrosis, haemorrhage and death [189]. In recent years, significant attention has been given to the ever rising problem of these cyanotoxins occurring in aquatic sources, especially those that serve as sources of drinking water supply [189][190][191][192][193][194][195][196][197][198][199][200][201]. Choi et al [202] in 2007 reported that when using a visible light active (VLA) N-TiO 2 material under acidic conditions (pH 3.5), the adsorption and photocatalytic degradation of MC-LR is greatly improved.…”

Quantitative analysis of poly- and perfluoroalkyl compounds in water matrices using high resolution mass spectrometry: Optimization for a laser diode thermal desorption method

“…Analytical runs are thus reduced by about twenty to fifty-fold compared with conventional LC-MS/MS methods. LDTD has been used in a number of analytical applications, for instance, in the determination of pharmaceutical residues in wastewater [19], dairy milk [20] and human plasma [21], steroid hormones [22] and pesticides [23] in wastewater, and cyanobacterial toxins in surface water [24]. However, since LDTD acquisition runs are about 9-s long, this usually does not allow for more than 6-8 transitions to be properly acquired at once when interfaced to a triple quadrupole (QqQ) mass spectrometer, due to dwell time limitations [23].…”