Total ocular, anterior corneal and lenticular higher order aberrations in hyperopic, myopic and emmetropic eyes

Abstract

Total ocular higher order aberrations and corneal topography of myopic, emmetropic and hyperopic eyes of 675 adolescents (16.9 ± 0.7 years) were measured after cycloplegia using COAS aberrometer and Medmont videokeratoscope. Corneal higher order aberrations were computed from the corneal topography maps and lenticular (internal) higher order aberrations derived by subtraction of corneal aberrations from total ocular aberrations. Aberrations were measured for a pupil diameter of 5mm. Multivariate analysis of variance followed by multiple regression analysis found significant difference in the fourth order aberrations (SA RMS, primary spherical aberration coefficient) between the refractive error groups. Hyperopic eyes (+0.083 ± 0.05 μm) had more positive total ocular primary spherical aberration compared to emmetropic (+0.036 ± 0.04 μm) and myopic eyes (low myopia=+0.038 ± 0.05 μm, moderate myopia=+0.026 ± 0.06 μm) (p<0.05). No difference was observed for the anterior corneal spherical aberration. Significantly less negative lenticular spherical aberration was observed for the hyperopic eyes (-0.038 ± 0.05 μm) than myopic (low myopia=-0.088 ± 0.04 μm, moderate myopia=-0.095 ± 0.05 μm) and emmetropic eyes (-0.081 ± 0.04 μm) (p<0.05). These findings suggest the existence of differences in the characteristics of the crystalline lens (asphericity, curvature and gradient refractive index) of hyperopic eyes versus other eyes.

Objective functional visual outcomes of cataract surgery in patients with good preoperative visual acuity

“…16,18,20,[23][24][25][26] Internal aberrations may better represent the lens-induced changes, which were all significantly increased compared with the cataract-free eyes reported previously. [27][28][29] Thus, the relatively aggravated wavefront results might imply the Specific components of wavefront analysis may also predict specific visual complaints. For example, in a prior report, glare was associated with the total HOA and spherical aberration, and double vision was mainly associated with coma.…”

Near Work–Induced Contrast Adaptation in Emmetropic and Myopic Children

“…[60][61][62] On balance, these are unlikely to constitute factors contributing to contrast adaptation or development of myopia.…”

Objective Optical Quality and Intraocular Scattering in Myopic Adults

“…Correlations between high-order aberrations and myopia are inconclusive. [4][5][6] Retinal straylight-related studies, in which a psychophysical method is used to measure the scattering, suggested that the scatter light increases with ocular axial length or myopic spherical equivalent. 7,8 In the present study, another objective and quantitative method based on the double-pass technique, the optical quality analysis system (OQAS), was used to characterize both retinal image quality and intraocular scattering in myopes of different levels.…”