Total phenolic and flavonoid contents of Anacyclus pyrethrum Link plant extracts and their Antioxidant activity

Elazzouzi, Hanane; Zekri, Nadia; Zair, Touriya; Belghiti, Mohamed Alaoui El

doi:10.33640/2405-609x.1269

Cited by 13 publications

(30 citation statements)

References 13 publications

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“…Since it is speculated that calorimetric assays may not be able to give a complete picture of the quality and quantity of different flavonoid and phenolic components in any extract [30], we underwent HPLC technique to validate the existence of phenolic and flavonoid components in the extracts (Table 2; Fig. 4).…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Euphorbia helioscopia in context to a possible connection between antioxidant and antidiabetic activities: a comparative study of different extracts

Mustafa

Faisal

Hussain

et al. 2021

BMC Complement Med Ther

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Background Euphorbia helioscopia, conventionally known as sun spurge, has been used as a traditional medicine to treat different diseases owing to its reported antitumor, antiviral and antioxidant activities. Methods The current research was formulated to assess the in-vitro antioxidant and antidiabetic ability of Euphorbia helioscopia subsequent to the phytochemical analysis of its various extracts. For this purpose, methanol, ethanol and aqueous extracts were prepared using the whole dried plant. Phytochemical analysis of the extracts was done to evaluate the total flavonoid components (TFC) and total phenolic components (TPC) in the extracts. A total of seven phenolic and three flavonoid contents were documented and quantified using HPLC. Antioxidant values were found by DPPH● assay, FRAP and ABTS assays. The antidiabetic potential of the extracts was evaluated by measuring the inhibition ability of the activity of enzymes α amylase and α glucosidase. Results After analyzing statistically, the results showed that methanolic extract possesses the highest TFC and TPC values while aqueous extract encompassed the lowest level of these contents. Invitro results showed that methanolic extract of the Euphorbia helioscopia has the maximum antioxidant capability since it showed the highest scavenging ability towards the DPPH● (IC50 value = 0.06 ± 0.02 mg/ml), FRAP (758.9 ± 25.1 μMFe+ 2/g), and ABTS (689 ± 25.94 μMTEq/g) due to the presence of high TPC (24.77 ± 0.35 mgGAEq/g) and TFC (17.95 ± 0.32 mgQEq/g) values. Antidiabetic activity in terms of inhibition potential of α amylase and α glucosidase activity was also observed maximum in methanolic extract having lowest IC50 value (0.4 ± 0.01 mg/ml and 0.45 ± 0.01 mg/ml respectively) and minimum in the aqueous extract (IC50 value = 0.57 ± 0.02 mg/ml and 0.76 ± 0.1 mg/ml respectively). Conclusion The experiment outcomes have shown that Euphorbia helioscopia extracts used in the current study contain antioxidant and antidiabetic activities; however, it is highest in its methanolic extract. The presence of the same trend towards the highest antidiabetic activity of the methanolic extract in terms of maximum inhibiting activity of α amylase and α glucosidase enzymes suggests a close association of TFC and TPC in minimizing diabetes.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Euphorbia helioscopia in context to a possible connection between antioxidant and antidiabetic activities: a comparative study of different extracts

Mustafa

Faisal

Hussain

et al. 2021

BMC Complement Med Ther

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show abstract

“…Whereas, in the TAC test, that the anthocyanins extracts appear better total antioxidant capacity. This difference in the scavenging activity between the extracts could be because of the structure, quality, and functional capability of those compounds in the tested samples (Chouikh et al, 2018;Elazzouzi et al, 2019). Where; the previous researches showed that phenolic compounds with ortho-and para-dihydroxylation, a hydroxy and or a methoxy group or both have stronger antioxidant activity than simple polyphenols and also the presence of double bond conjugated and ketone groups in the whole molecule might play different polarities in the structure of the antioxidants and can be attributed to their antioxidant activity (Heshmati Afshar et al, 2012;Sroka, 2005).…”

Section: Discussionmentioning

confidence: 99%

Comparative study of some physicochemical and biological properties of effect host species variation on the relationship Saharan parasitic plant Cistanche violaceae (Desf.) Beck.

ALIA¹,

Chouikh²,

Djahra³

et al. 2021

Not Sci Biol

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This work aims to study the effect of different host species on physicochemical and biological properties of the Saharan parasitic plant Cistanche violacea that grows parasitized on two hosts Haloxylon articulatum and a Limonistrum guyonianum in the eastern desert of Algeria. The physicochemical characteristics of C. violcea showed an affinity for the results of both ash and pH and it showed a difference in the amount content of carbohydrates and the value of electrical conductivity. For the content of polyphenols, flavonoids, anthocyanins and tannins the highest values were recorded in C. violcea, which was parasitized on H. articulatum. While, the results of HPLC have identified nine compounds in the crude extracts of the parasitic plants and their hosts in different concentrations. In antioxidant activity, the tannin and anthocyanin extracts from C. violcea parasitized on H. articulatum showed better inhibition of DPPH• radical and best the total antioxidant capacity respectively, but the tannins extract of C. violcea parasitized on L. guyonianum given best reducing power capacity. In SPF assay by UV-Vis spectrophotometry method, all extracts of the parasitic plants showed mild to moderate sun protection. Statically the host variation did not show any significant differences in the physicochemical analysis and the quantitative and qualitative total content of polyphenols. While the significant differences appeared through the antioxidant activity tests, especially between C. violcea and its host H. articulatum, between C. violacea and its host H. articulatum and between the two samples of parasitic plants.

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“…The search for natural antioxidants has been the subject of several studies on A. pyrethrum ( Table 2 ) [ 6 , 8 , 39 , 45 , 46 ]. In a previous study, the author and his collaborators studied the antioxidant potency of the MeOH ext., the Aqu.…”

Section: Biological and Pharmacological Actionsmentioning

confidence: 99%

“…recorded an antioxidant effect with IC 50 of 13.41, 60.17 and 120.66 μg/mL, respectively. In addition, Elazzouzi et al [ 45 ] studied the antioxidant efficacy of the A. pyrethrum root extracts from the Timatidite region, Morocco. They reported that the MeOH ext., BuOH fra., AcEth fra.…”

Section: Biological and Pharmacological Actionsmentioning

confidence: 99%

Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review

Elazzouzi

Fadili²,

Cherrat³

et al. 2022

Plants

Self Cite

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Anacyclus pyrethrum (L.) (Asteraceae) is an important annual medicinal herb and is widespread in Morocco and Algeria. Most of its parts are used in traditional medicine and the roots are the most important parts used. The present review gives an account of the updated information on its phytochemical and pharmacological properties. We have collected the essential characteristics and the different scientific data of the A. pyrethrum species, and reviewed its potential. It is seen from the literature that A. pyrethrum is a rich source of the phytochemical constituents such as alkaloids (pellitorin) and n-alkylamides. This species also contains pyrethrins, sesamin, traces of essential oils and a wide range of other chemical compounds. These active substances possess antimicrobial and anti-inflammatory activities. The plant has an antidiabetic, insecticidal and immunostimulatory effect, as well as an aphrodisiac and antioxidant potentials, and various other important medicinal properties. Many traditional uses are also reported in previous research such as for rheumatism, sciatica, colds, neuralgia and paralysis. This species is considered to be a sialagogue, and used in the treatment of stomach ailments, diseases of inflammation of the mouth, against cysts in the genital tract and to relieve toothaches. Thus, further research must be carried out in order to establish any relationship between the traditional uses, phytochemistry and toxicity. Moreover, A. pyrethrum is quite promising as a medicinal agent, so further clinical trials should be performed to prove its efficacy.

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Total phenolic and flavonoid contents of Anacyclus pyrethrum Link plant extracts and their Antioxidant activity

Abstract: Total phenolic and flavonoid contents of Anacyclus pyrethrum Link plant extracts Total phenolic and flavonoid contents of Anacyclus pyrethrum Link plant extracts and their Antioxidant activity and their Antioxidant activity

Cited by 13 publications

References 13 publications

Efficacy of Euphorbia helioscopia in context to a possible connection between antioxidant and antidiabetic activities: a comparative study of different extracts

Efficacy of Euphorbia helioscopia in context to a possible connection between antioxidant and antidiabetic activities: a comparative study of different extracts

Comparative study of some physicochemical and biological properties of effect host species variation on the relationship Saharan parasitic plant Cistanche violaceae (Desf.) Beck.

Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review

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