Total Synthesis of Both Enantiomers of Dictyochromenol and their (<i>Z</i>)-Isomers

Aoki, Katsuhiko; Takahashi, Mihoko; Hashimoto, Minoru; Okuno, Toshikatsu; Kurata, K.; Suzuki, Minoru

doi:10.1271/bbb.66.1915

Cited by 9 publications

(8 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…143 S. carpophyllum from the South China Sea was the source of two new bioactive sterols 138 and 139. 154 A total synthesis of yahazunol, originally isolated from the brown alga Dictyopteris undulata, 155 has been achieved, starting from (ϩ)-albicanic acid. 144 S. polycystum collected in the North China Sea yielded a new sterol, stigmast-5,23,25-triene 140.…”

Section: Brown Algaementioning

confidence: 99%

Marine natural products

et al. 2004

View full text Add to dashboard Cite

This review covers the literature published in 2002 for marine natural products, with 579 citations (413 for the period January to December 2002) referring to compounds isolated from marine microorganisms and phytoplankton, green algae, brown algae, red algae, sponges, coelenterates, bryozoans, molluscs, tunicates and echinoderms. The emphasis is on new compounds (677 for 2002), together with their relevant biological activities, source organisms and country of origin. Syntheses that lead to the revision of structures or stereochemistries have been included (114), including any first total syntheses of a marine natural product.

show abstract

Section: Brown Algaementioning

confidence: 99%

Marine natural products

et al. 2004

View full text Add to dashboard Cite

show abstract

“…The antimicrobial glycolipid caminoside-A, isolated from Dominican specimens of Caminus sphaeroconia , was found to be a potent inhibitor of the bacterial type-III secretion system [71]. Lembehynes B and C, isolated from an Indonesian species of Haliclona , were found to possess neuritogenic activity against neuroblastoma cells [72]. …”

Section: Metabolites From Spongesmentioning

confidence: 99%

Biomedical Compounds from Marine organisms

2004

View full text Add to dashboard Cite

Abstract:The Ocean, which is called the 'mother of origin of life', is also the source of structurally unique natural products that are mainly accumulated in living organisms. Several of these compounds show pharmacological activities and are helpful for the invention and discovery of bioactive compounds, primarily for deadly diseases like cancer, acquired immuno-deficiency syndrome (AIDS), arthritis, etc., while other compounds have been developed as analgesics or to treat inflammation, etc. The lifesaving drugs are mainly found abundantly in microorganisms, algae and invertebrates, while they are scarce in vertebrates. Modern technologies have opened vast areas of research for the extraction of biomedical compounds from oceans and seas.

show abstract

“…As described herein, the 1,4-dialkyn-3-ol part, jointly to the stereochemistry at the hydroxy position, are implicated in the bioactivity of these hydroxylated polyacetylenes [31,32,33,38]. As described herein, the 1,4-dialkyn-3-ol part, jointly to the stereochemistry at the hydroxy position, are implicated in the bioactivity of these hydroxylated polyacetylenes [31,32,33,38].…”

Section: Studies In Natural Products Chemistrymentioning

confidence: 61%

“…The linear C 36 diacetylenic alcohol, lembehyne A (19A), was isolated from an Indonesian Haliclona sp [30]. 21) Compared to lembehyne A, lembehyne B and C have different long carbonchains but also exhibited neuritogenic activity against the neuroblastoma cell line Neuro 2A [31]. 21) Compared to lembehyne A, lembehyne B and C have different long carbonchains but also exhibited neuritogenic activity against the neuroblastoma cell line Neuro 2A [31].…”

Section: Haliclonamentioning

confidence: 99%