Total Thyroidectomy for Benign Thyroid Diseases: What is the Price to be Paid?

Gangappa, Rajashekara Babu; Kenchannavar, Manjunath Basavaraj; Chowdary, Prashanth Basappa; Patanki, Adithya Malolan; Ishwar, M.

doi:10.7860/jcdr/2016/18733.7991

Cited by 15 publications

(24 citation statements)

References 21 publications

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“…However, there remains some debate about the suitability of thyroidectomy in the treatment of some diseases because of the risk of complications. [ 3 ] The most significant operative complications include injury to the recurrent or superior laryngeal nerve and to the parathyroid glands. Devascularization, trauma, and inadvertent removal of 1 or more parathyroid glands will probably result in hypoparathyroidism and hypocalcemia; however, the cause of postoperative hypocalcemia is multifactorial, and can be transient or permanent.…”

Section: Introductionmentioning

confidence: 99%

“…The associated morbidity of these complications includes hypocalcemia symptoms such as perioral numbness and tingling in the fingers, and also calcification of basal ganglia and renal impairment. [ 3 ] Postoperative hypocalcemia increases the use of medicine and biochemical tests, and results in a prolonged hospital stay, and so adds to the overall cost of thyroidectomy. [ 5 ] Incidental parathyroidectomy during thyroidectomy occurs at a rate between 5.2% and 21.6%, depending mainly on the surgeon's experience, [ 6 ] although the risk is not completely eliminated in the hands of high-case-volume endocrine surgeons.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of clinical significance and risk factors of incidental parathyroidectomy due to thyroidectomy

et al. 2017

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We assessed the clinical significance and risk factors of incidental parathyroidectomy during total thyroidectomy with or without central neck dissection or subtotal thyroidectomy.Retrospective analysis of clinical and pathological features of 548 consecutive thyroidectomy cases was compared by grouping into inadvertent resection (IR, n = 86) with IR of parathyroid glands, non-IR (n = 462) without, and then into postoperative hypoparathyroidism (PH, n = 140) with PH and non-PH (n = 408) without.Two hundred ninety-eight patients had total thyroidectomy and 250 had subtotal thyroidectomy. IR had higher malignant disease (P < .001), total thyroidectomy (P = .016), T3 and T4 classification (P = .005), central neck dissection (P < .001), recurrent laryngeal nerve palsy (P = .003), postoperative transient hypoparathyroidism (P < .001), duration of disease prior to thyroidectomy (P < .001), and weight of excised thyroid tissue (P < .001) than non-IR.Preoperative diagnosis of malignant disease, duration of disease prior to thyroidectomy, and central neck dissection were independent risk factors for incidental parathyroidectomy. Preoperative diagnosis of malignant disease, central neck dissection, duration of disease prior to thyroidectomy, weight of excised thyroid tissue, and incidental parathyroidectomy were correlated with PH.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of clinical significance and risk factors of incidental parathyroidectomy due to thyroidectomy

et al. 2017

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“…Especially when compared with primary TT; the rate of complications up to 5-10 times for permanent recurrent nerve paralysis and persistent hypoparathyroidism is quite striking [32][33][34]. On the other hand, no significant difference was reported between the patients who underwent TT for the first operation due to benign MNG and those who underwent subtotal thyroidectomy [35][36].…”

Section: Discussionmentioning

confidence: 99%

Incidental thyroid cancer in patients undergoing surgery for benign multinodular goitre: A retrospective clinical study

zpek¹,

Topal²

2019

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“…The pressure complaints, shorter complaining period, malignancy and more radical surgeries are the factors influencing thyroidectomy complications [3]. The risk of permanent complications is high in patients who performed surgery for the recurrence of benign thyroid disease [6]. Total thyroidectomy is considered as the treatment of choice for various thyroid diseases except in case of thyroid carcinoma and a few benign diseases due to its risk involved [1].…”

Section: Introductionmentioning

confidence: 99%

“…It is performed mainly in malignant thyroid disease as it can reduce the rate of recurrence and reoperations. The risk of recurrence is high with subtotal thyroidectomy performed for benign thyroid diseases [6].…”

Section: Introductionmentioning

confidence: 99%

Profile and complication rate of thyroid surgeries performed in a tertiary care teaching hospital, a prospective observational study

Sathiah

Chandrabose

2019

Int J Surg Ortho

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Background: One of the most common endocrine disorder is the thyroid diseases. The prevalence and pattern of these conditions depends on sex, age, ethnic and geographic patterns. The incidence of thyroid nodules increases with the age hence benign and malignant thyroid disease is common in the elderly population. Aim: To compare the complication rate of various thyroid surgeries for benign and malignant diseases in a tertiary care teaching hospital. Methods: This study was a prospective observational study, Velammal medical college hospital at Tamil Nadu from December 2018-June 2019. The patients who underwent thyroid surgery for various thyroid disorders were enrolled in the study. Results: Out of117 cases, 107 were women and 10 were men. Multinodular goiter (MNG)was the most common (38.46%) condition, followed by solitary nodule (29.06%) and toxic MNG (18.8%). Among women, 40.19% were identified with multinodular goiter followed by solitary nodule (28.97%). Subtotal thyroidectomy was performed for 88.89% of MNGs, while 91.18% of the solitary nodule were managed by hemithyroidectomy Majority of the patients with toxic MNG underwent subtotal thyroidectomy with 99.91%. While 84.61% of the patients with thyroid cancer were treated by total thyroidectomy. The overall incidence of complications was 27.35%. The incidence rate of complications was high in patients with malignant disease, as compared to benign disease (69.23% in Malignant Vs 36.36% in toxic MNG and 24.44% in MNG). Conclusion: Through the present study, it was concluded that the complications associated with the different thyroid surgeries and various precautions that can be taken to reduce the complications.

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Total Thyroidectomy for Benign Thyroid Diseases: What is the Price to be Paid?

Cited by 15 publications

References 21 publications

Evaluation of clinical significance and risk factors of incidental parathyroidectomy due to thyroidectomy

Evaluation of clinical significance and risk factors of incidental parathyroidectomy due to thyroidectomy

Incidental thyroid cancer in patients undergoing surgery for benign multinodular goitre: A retrospective clinical study

Profile and complication rate of thyroid surgeries performed in a tertiary care teaching hospital, a prospective observational study

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