Tourette's Syndrome in Patients Referred for Allergy Evaluation

Attention deficit hyperactivity disorder, tic disorder, and allergy: is there a link? A nationwide population‐based study

“…Caine et al found no evidence for a linkage between a gene locus determining susceptibility to tic disorder and the HLA loci (Caine et al, 1985). However, in clinical practice, the comorbidity of allergy and tic disorder is usually noted (Chang et al, 2011;Finegold, 1985;Kim, Moote, & Mazza, 1997). Some evidence has supported the cytokines hypothesis regarding tic disorder (Bos-Veneman et al, 2010;Leckman et al, 2005;Martino, Dale, Gilbert, Giovannoni, & Leckman, 2009;Morer et al, 2010).…”

Correlation of Tourette Syndrome and Allergic Disease: Nationwide Population-Based Case-Control Study

“…[15][16][17][18][19] Ho et al 15 cited patients who show clinical evidence of allergy in the Multiple Allergens Simultaneous Tests positive group (56.9%) of patients with TS as displaying a significant difference from controls. Prevalence of allergy in patients with TS has proven significantly higher than in the general population.…”

Current issues in Tourette syndrome

“…[6][7][8][9][10] In nine patients with TS, the blink rate was approximately two-to threefold higher at rest than the blink rate of control subjects. Task-specific events were shown to affect eye blinks and ocular tics; eye blinks were increased by watching videos but not by conversation, whereas ocular tics were generally increased while watching amusing videos but decreased during active involvement in conversation.…”