“…Nerve injury tends to be greater beneath the tourniquet than distal to it, due to the combined effects of ischemia and direct mechanical deformation (Denny-Brown and Brenner 1944, Moldaver 1954, Lundborg 1970, Fowler et al 1972, Ochoa et al 1972, Rudge 1974, Bolton and McFarlane 1978, Rorabeck 1980, Rorabeck and Kennedy 1980, Yates et al 1981, Nitz 1982. Relatively little information is available regarding critical pressure and time limits for muscle injury induced by pneumatic tourniquet compression (Patterson and Klenerman 1979, Patterson et al 1981, Gersoff et al 1989.…”