Toward the institutionalization of quantum computing in pharmaceutical research

Zinner, Maximillian; Dahlhausen, Florian; Boehme, Philip; Ehlers, Jan P.; Bieske, Linn; Fehring, Leonard

doi:10.1016/j.drudis.2021.10.006

Cited by 23 publications

(9 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At the same time, quantum computing can be used in the manufacturing, supply chain, and other use of drug distribution. Zinner et al proposed a plan for using quantum computing along with the CADD and AI during drug discovery, development, and distribution [ 4 ]. Recently, Lau et al enriched the drug discovery and development area by inventing a hybrid classical quantum workflow model for drug design entitled HypaCADD.…”

Section: Applications Of Quantum Computing To Understand the Next-gen...mentioning

confidence: 99%

“…Therefore, in the same space, speedy supercomputing and enormous parallel computing facilities are the need of the present day, which is changing the present scenario of computational resources and creating entirely new computing paradigms. Now, quantum computing (QC) has developed a plethora of ways to address modern biological problems and complex biological questions [ 1 – 4 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Quantum Computing in the Next-Generation Computational Biology Landscape: From Protein Folding to Molecular Dynamics

et al. 2023

View full text Add to dashboard Cite

Modern biological science is trying to solve the fundamental complex problems of molecular biology, which include protein folding, drug discovery, simulation of macromolecular structure, genome assembly, and many more. Currently, quantum computing (QC), a rapidly emerging technology exploiting quantum mechanical phenomena, has developed to address current significant physical, chemical, biological issues, and complex questions. The present review discusses quantum computing technology and its status in solving molecular biology problems, especially in the next-generation computational biology scenario. First, the article explained the basic concept of quantum computing, the functioning of quantum systems where information is stored as qubits, and data storage capacity using quantum gates. Second, the review discussed quantum computing components, such as quantum hardware, quantum processors, and quantum annealing. At the same time, article also discussed quantum algorithms, such as the grover search algorithm and discrete and factorization algorithms. Furthermore, the article discussed the different applications of quantum computing to understand the next-generation biological problems, such as simulation and modeling of biological macromolecules, computational biology problems, data analysis in bioinformatics, protein folding, molecular biology problems, modeling of gene regulatory networks, drug discovery and development, mechano-biology, and RNA folding. Finally, the article represented different probable prospects of quantum computing in molecular biology. Supplementary Information The online version contains supplementary material available at 10.1007/s12033-023-00765-4.

show abstract

Section: Applications Of Quantum Computing To Understand the Next-gen...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Quantum Computing in the Next-Generation Computational Biology Landscape: From Protein Folding to Molecular Dynamics

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Financial problems like risk modeling, derivate pricing, fraud detection, and portfolio management are hoped to be solved (Ali, Yue and Abreu 2022;Egger et al 2020;Ganapathy 2021;Herman et al 2022;Srivasta et al 2016). Quantum applications could also be used in the logistics sector with scheduling applications (Hassija et al 2020;Srivasta et al 2016), in the health sector for the acceleration of disease research and drug development (Ali, Yue and Abreu 2022;Srivasta et al 2016;Zinner et al 2022), and in the software development sector for more efficient software tests to minimize the costs of software errors (Srivasta et al 2016). The prospect of quantum simulations (Hassija et al 2020) is relevant for many sectors like airplane manufacturing (Srivasta et al 2016) or chemistry (Cheng et al 2020;Outeiral et al 2021;Zinner et al 2022).…”

Section: Possible Benefits Of Quantum Computers For Companiesmentioning

confidence: 99%

“…Quantum applications could also be used in the logistics sector with scheduling applications (Hassija et al 2020;Srivasta et al 2016), in the health sector for the acceleration of disease research and drug development (Ali, Yue and Abreu 2022;Srivasta et al 2016;Zinner et al 2022), and in the software development sector for more efficient software tests to minimize the costs of software errors (Srivasta et al 2016). The prospect of quantum simulations (Hassija et al 2020) is relevant for many sectors like airplane manufacturing (Srivasta et al 2016) or chemistry (Cheng et al 2020;Outeiral et al 2021;Zinner et al 2022). The conceivable scenarios for use cases of quantum computers are manifold and depend on the company under consideration.…”

Section: Possible Benefits Of Quantum Computers For Companiesmentioning

confidence: 99%

The Outlook of German Companies on IT-Security and Their Readiness for Quantum Computing

Schindler¹

2022

Proceedings of the 5th International Conference on Advanced Research in Social Sciences

View full text Add to dashboard Cite

Quantum computers are currently in development. As soon as they are available for widespread use, they can offer great benefits for companies. However, they can also pose dangers to information security. Because of this, protection measures are needed. To gain an insight into the outlook and knowledge of companies on quantum computing and their internal decision processes when establishing new technologies, qualitative interviews were conducted. Because not all companies know about quantum computing, the questions were designed without necessary previous knowledge in mind. Additionally, an employee of the German Federal Office for Information Security (BSI) was asked for their opinions. Many of the interviewed companies were not well informed about quantum computing and some lacked preparation of their general IT security. However, they had ideas how they could utilize such a much more powerful computer in the future. To gauge how quantum-secure measures could be implemented among companies, the companies were asked about their decision criteria when deciding on implementing a new technology. Their answers often included price and distribution, functions of the technology and external influences like other companies or guidelines from the government. To support the transition to quantum computer-safe cryptography in companies, different areas of action are examined. Supporting the availability of relevant use cases, market incubation and standards, collaboration between companies and education among them can help in pushing the spread of post-quantum security in companies in the future.

show abstract

“…The massive increase in computational capacity is not only beneficial for healthcare IoT but can allow quantum computers to enable fundamental breakthroughs in this domain. When we leap from bits to qubits, it could improve healthcare pharmaceutical research (4), which includes analyzing the folding of proteins, determining how molecular structures for instance drug and enzyme fit together (5), determining strengths of binding interactions between a single biomolecule for example protein or DNA to its ligand/binding partner like a drug or inhibitor. (6), and accelerating the process of clinical trials (7).…”

Section: A Introduction To Quantum Computingmentioning

confidence: 99%

Quantum Computing for Healthcare: A Review

Rasool¹,

Ahmad²,

Rafique³

et al. 2023

Preprint

View full text Add to dashboard Cite

<p>Classical computing works by processing bits, or 0s and 1s representing electrical signals of on and off. Quantum computing employs a very different technique for information processing. It uses qubits, which can exist as both a 1 and 0 at the same time, and uses the properties of subatomic particles in quantum physics such as interference, entanglement, and superposition to extend computational capabilities to hitherto unprecedented levels. The efficacy of quantum computing for important verticals such as healthcare where quantum computing can enable important breakthroughs in the development of life-saving drugs, performing quick DNA sequencing, detecting diseases in early stages, and performing other compute-intensive healthcare related tasks is not yet fully explored. Furthermore, implementations of quantum computing for healthcare scenarios such as these have their own unique set of requirements. Unfortunately, existing literature that address all of these dimensions is largely unstructured. This research is intended to be the first systematic analysis of the capabilities of quantum computing in enhancing healthcare systems. This article is structured with the help of taxonomies developed from existing literature to provide a panoramic view of the background and enabling technologies, applications, requirements, architectures, security and open issues, and future research directions. We believe the paper will aid both new and experienced researchers working in both quantum computing and the healthcare domains in visualizing the diversity in current research, in better understanding both pitfalls and opportunities, and coming up with informed decisions when designing new architectures and applications for quantum computing in healthcare.</p>

show abstract

Toward the institutionalization of quantum computing in pharmaceutical research

Cited by 23 publications

References 26 publications

Quantum Computing in the Next-Generation Computational Biology Landscape: From Protein Folding to Molecular Dynamics

Quantum Computing in the Next-Generation Computational Biology Landscape: From Protein Folding to Molecular Dynamics

The Outlook of German Companies on IT-Security and Their Readiness for Quantum Computing

Quantum Computing for Healthcare: A Review

Contact Info

Product

Resources

About