This study examined research centre Biosphere 2 (B2) coverage by US newspapers between 1984 (as stories of conception before construction emerged) and 2019 (at the time this research was conducted) in order to uncover news diffusion relative to B2 in public media across historic eras and amid shifts in stakeholders over time. The analysis focussed on how a scientific institution and its innovative activities implied values, impacted the meaning-making of its project, as well as influenced the amount of information shared across sources (i.e., regional, metropole or elite) and media scale (i.e., local, regional, national outlets). This analysis identified nine eras delimited by scientific or organisational events. The findings emerging from this study can inform understandings of media behaviour around other scientific institutions and experiments.