Toxic Encephalopathies

Eicher, Tracy J.; Avery, Eleanor

doi:10.1016/j.ncl.2004.12.004

Cited by 7 publications

(2 citation statements)

References 81 publications

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“…In Iraq, the consumption of wheat and barley seed sprayed with a mercury fungicide also led to considerable morbidity and mortality. As much current exposure to mercury occurs through the intake of contaminated seafood (21), concern has been expressed in the medical literature about the potential encephalopathic state induced by mercury and other brain toxicants (22).…”

Section: Discussionmentioning

confidence: 99%

Toxicant Exposure and Mental Health—Individual, Social, and Public Health Considerations

Genuis

2009

Journal of Forensic Sciences

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Thoughts and moods are the result of biological processes; disordered thoughts and moods may be the result of disordered biological processes. As brain dysfunction can manifest with emotional symptoms or behavioral signs, the etiology of some mental health afflictions and some abnormal conduct is pathophysiological rather than pathopsychological. Various studies confirm that some chemical toxicants which modify brain physiology have the potential to affect mood, cognitive function, and to provoke socially undesirable outcomes. With pervasive concern about myriad chemical agents in the environment and resultant toxicant bioaccumulation, human exposure assessment has become a clinically relevant area of medical investigation. Adverse exposure and toxicant body burden should routinely be explored as an etiological determinant in assorted health afflictions including disordered thinking, moods, and behavior. The impact of toxicant bioaccumulation in a patient with neuropsychiatric symptoms is presented for consideration as an example of the potential benefit of recognizing and implementing exposure assessment.

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Section: Discussionmentioning

confidence: 99%

Toxicant Exposure and Mental Health—Individual, Social, and Public Health Considerations

Genuis

2009

Journal of Forensic Sciences

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“…[4849] Arsenic inhibits mitochondrial function and interferes with oxidative metabolism in neurons. [50] Some improvement of symptoms may follow removal of the exposure.…”

Section: Toxinsmentioning

confidence: 99%

Endocrine, metabolic, nutritional, and toxic disorders leading to dementia

Ghosh

2010

Ann Indian Acad Neurol

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One of the first steps toward the correct diagnosis of dementia is to segregate out the nondegenerative dementias from possible degenerative dementias. Nondegenerative dementias could be due to traumatic, endocrine, metabolic, nutritional, toxic, infective, and immunological causes. They could also be caused by tumors, subdural hematomas, and normal pressure hydrocephalus. Many of the nondegenerative dementias occur at an earlier age and often progress quickly compared to Alzheimer’s disease and other degenerative dementias. Many are treatable or preventable with simple measures. This review aims to give an overview of some of the more important endocrine, metabolic, nutritional, and toxic disorders that may lead to dementia.

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