Toxicidade De Bebidas Lácteas Achocolatadas Do Tipo Não Fermentadas Em Tecido De Intensa Proliferação Celular

Martins, Hélia Alencar; Peron, Ana Paula

doi:10.5902/2179460x23953

Cited by 1 publication

(1 citation statement)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The root meristem of Allium cepa L. is considered an efficient test system for the initial screening of the cytotoxicity and genotoxicity of chemical compounds, occupying a prominent position among the set of tests used in the preliminary evaluation of cytotoxotoxic agents (HERRERO et al, 2012;MARTINS;PERON, 2017). The efficiency of the bioassay is mainly because this species presents few chromosomes (2n = 16), which favors the detection of disorders in the cell proliferation index, and cellular alterations, such as mitotic spindle disturbances and chromosomal breaks (NEVES et al, 2014;SALES et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Cytotoxic and genotoxic potential of Ginkgo biloba L., in industrialized and without-additive forms

Guedes¹,

Santos²,

Silva³

et al. 2018

Biosci. J.

View full text Add to dashboard Cite

The toxic potential at the cellular level of industrialized Ginkgo biloba L. leaves was evaluated in meristematic cells of Allium cepa at concentrations of 0.1; 0.2 and 0.4 mg/ml. The industrialized products, from four pharmaceutical laboratories, were identified as A, B, C and D. Cell-level toxicity of dehydrated ginkgo leaf tea was also evaluated at concentrations of 0.15; 0.30 and 0.60 mg/ml. Dehydrated products were purchased from herbalists certified by ANVISA. The roots were exposed to teas and processed products for 24 and 48 hours. The results were submitted to the Chi-square test at 5%. However, industrialized ginkgo products at all concentrations caused antiproliferative effect. Also, the products purchased in pharmacies did not induce significant changes to root meristems. Therefore, industrialized ginkgo promoted cytotoxicity, however, they were not genotoxic to the bioassay used.

show abstract

Section: Introductionmentioning

confidence: 99%

Cytotoxic and genotoxic potential of Ginkgo biloba L., in industrialized and without-additive forms

Guedes¹,

Santos²,

Silva³

et al. 2018

Biosci. J.

View full text Add to dashboard Cite

show abstract

Toxicidade De Bebidas Lácteas Achocolatadas Do Tipo Não Fermentadas Em Tecido De Intensa Proliferação Celular

Abstract: Resumo Objetivou-se nesse trabalho avaliar a toxicidade aguda em nível celular de bebidas lácteas achocolatadas de cinco

Cited by 1 publication

References 16 publications

Cytotoxic and genotoxic potential of Ginkgo biloba L., in industrialized and without-additive forms

Cytotoxic and genotoxic potential of Ginkgo biloba L., in industrialized and without-additive forms

Contact Info

Product

Resources

About