Toxicity and accumulation of Copper oxide (CuO) nanoparticles in different life stages of Artemia salina

Madhav, Madurantakam Royam; David, Einstein Mariya; Kumar, Ritesh; Swathy, J S; Bhuvaneshwari, M.; Mukherjee, Amitava; Chandrasekaran, N.

doi:10.1016/j.etap.2017.03.013

Cited by 79 publications

(29 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The morphological changes and the accumulation of material in Artemia nauplii were observed by light microscopy (Leica DM 2500 microscope) in the light field (Madhav et al 2017). After exposure to the environment of interest, the organisms were transferred to a glass plate and were observed in 200-fold magnification under the optical microscope.…”

Section: Lethality Of Artemia Salina Nauplii Evaluationmentioning

confidence: 99%

Toxicity evaluation of process water from hydrothermal carbonization of sugarcane industry by-products

Fregolente

Miguel

et al. 2018

Environ Sci Pollut Res

View full text Add to dashboard Cite

Hydrothermal carbonization (HTC) is a thermochemical process carried out in an aqueous medium. It is capable of converting biomass into a solid, carbon-rich material (hydrochar), and producing a liquid phase (process water) which contains the unreactive feedstock and/or chemical intermediates from the carbonization reaction. The aim of this study was to evaluate the characteristics of process water generated by HTC from vinasse and sugarcane bagasse produced by sugarcane industry and to evaluate its toxicity to both marine (using Artemia salina as a model organism) and the terrestrial environment (through seed germination studies of maize, lettuce, and tomato). The experiments showed that concentrated process water completely inhibited germination of maize, lettuce, and tomato seeds. On the other hand, diluted process water was able to stimulate seedlings of maize and tomato and enhance root and shoot growth. For Artemia, the LC indicated that the process water is practically non-toxic; however, morphological changes, especially damages to the digestive tube and antennas of Artemia, were observed for the concentration of 1000 mg C L.

show abstract

Section: Lethality Of Artemia Salina Nauplii Evaluationmentioning

confidence: 99%

Toxicity evaluation of process water from hydrothermal carbonization of sugarcane industry by-products

Fregolente

Miguel

et al. 2018

Environ Sci Pollut Res

View full text Add to dashboard Cite

show abstract

“…A test was conducted on Tetrahymena thermophile to quantify the size-dependent toxic impact of copper oxide NPs (CuO-NPs), which showed that CuO-NPs were 10-20 times more toxic than its bulk form (Mortimer, Kasemets, & Kahru, 2010). The administration of CuO-NPs to Artemia salina revealed an alteration in biochemical markers, such as catalase (CAT), reduced glutathione (GSH) and glutathione-S-transferase activities (Madhav et al, 2017). The results of the examination of effects of CuO-NPs and zinc oxide NPs in Daphnia magna showed an increase in the levels of oxidized glutathione, increased thiobarbituric acid reactive substances formation, increased metallothionein induction and decreased glutathione-S-transferase activity (Mwaanga, Carraway, & van den Hurk, 2014).…”

mentioning

confidence: 99%

Acute and subacute oral toxicity of copper oxide nanoparticles in female albino Wistar rats

Bugata

Venkata

Gundu

et al. 2019

J of Applied Toxicology

View full text Add to dashboard Cite

The extensive use of copper oxide nanoparticles (CuO‐NPs) in various industries and their wide range of applications have led to their accumulation in different ecological niches of the environment. This excess exposure raises the concern about its potential toxic effects on various organisms including humans. However, the hazardous potential of CuO‐NPs in the literature is elusive, and it is essential to study its toxicity in different biological models. Hence, we have conducted single acute dose (2000 mg/kg) and multiple dose subacute (30, 300 and 1000 mg/kg daily for 28 days) oral toxicity studies of CuO‐NPs in female albino Wistar rats following OECD guidelines 420 and 407 respectively. Blood analysis, tissue aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and acetylcholinesterase, superoxide dismutase, catalase, lipid malondialdehyde and reduced glutathione assays, and histopathology of the tissues were carried out. The higher dose treatments of the acute and subacute study caused significant alterations in biochemical and antioxidant parameters of the liver, kidney and brain tissues of the rat. In addition, histopathological evaluation of these three organs of treated rats showed significantly high abnormalities in their histoarchitecture when compared to control rats. We infer from the results that the toxicity observed in the liver, kidney and brain of treated rats could be due to the increased generation of reactive oxygen species by CuO‐NPs.

show abstract

“…Nauplii (a larval stage of Artemia) have been used as biocarriers for feeding in diverse species such as coral, fish, and shrimp [22,23], for the encapsulation of supplements as probiotics, prebiotics, and symbiotic [24], for antibiotics [25], vaccines [26], and liposomes [27]. In addition, nauplii are used to transport inorganic (CuO, Ag, TiO 2 , and AgTiO 2 ) nanomaterials; in general, nauplii can be used as biological model nanotoxicology assays [28][29][30][31][32]. Other biocarriers for metallic NP include yeast cells (Ag and Pd) [10], magnetotactic bacteria [33], and bacterial ghost, which uses only some functions of microorganisms to transport nanomaterials as the outer membrane of gram-negative bacteria [34].…”

Section: Introductionmentioning

confidence: 99%

Silver Nanoparticles Synthesized with Rumex hymenosepalus: A Strategy to Combat Early Mortality Syndrome (EMS) in a Cultivated White Shrimp

Alvarez-Cirerol

López-Torres

Rodríguez-León

et al. 2019

Journal of Nanomaterials

View full text Add to dashboard Cite

Early Mortality Syndrome (EMS) or Acute Hepatopancreatic Necrosis Syndrome (AHPNS) is a disease produced by gram-negative bacteria Vibrio parahaemolyticus (V. parahaemolyticus), which has caused declines in worldwide production of a white shrimp Litopenaeus vannamei (L. vannamei). In this work, we propose the implementation of silver nanoparticles (AgNPs) synthesized with Rumex hymenosepalus (Rh) extract as an alternative on V. parahaemolyticus control. AgNPs were characterized by UV-Vis spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and selected area electron diffraction (SAED). AgNP mean sizes by DLS were 80.82±1.16 nm and sizes between 2 and 10 nm by TEM, with a zeta potential of −47.72±1.05 mV. This study evaluated AgNPs and Rh antimicrobial capacity on V. parahaemolyticus at different concentrations; the minimum inhibitory concentration (MIC) found was 25 μg/mL for AgNPs and 220 μg/mL for Rh. Additionally, were carried out time-kill curves and reactive oxygen species (ROS) generation for 1 and 4 MIC. Both concentrations (MIC) were tested for toxicity on Artemia nauplii from Artemia franciscana (A. franciscana), because nauplii were used as biocarriers for AgNPs and Rh extract on L. vannamei. Once the shrimp were treated, they were challenged with Vibrio infection and it was found that those who were treated with both agents showed greater survival than the control. V. parahaemolyticus and postlarval samples were taken from the bioassay and fixed and prepared for TEM and SEM in order to search NPs in internal structure of bacteria and the hepatopancreatic area of shrimps; AgNPs were detected in both cases. AgNPs and Rh extract show antibacterial properties on the infected shrimp with V. parahaemolyticus. The action mechanisms are interaction with the bacterial membrane and ROS generation; these effects are produced by both agents.

show abstract

Toxicity and accumulation of Copper oxide (CuO) nanoparticles in different life stages of Artemia salina

Cited by 79 publications

References 57 publications

Toxicity evaluation of process water from hydrothermal carbonization of sugarcane industry by-products

Toxicity evaluation of process water from hydrothermal carbonization of sugarcane industry by-products

Acute and subacute oral toxicity of copper oxide nanoparticles in female albino Wistar rats

Silver Nanoparticles Synthesized with Rumex hymenosepalus: A Strategy to Combat Early Mortality Syndrome (EMS) in a Cultivated White Shrimp

Contact Info

Product

Resources

About