Toxicity and bioaccumulation of biosolids-borne triclocarban (TCC) in terrestrial organisms

Field dissipation and risk assessment of typical personal care products TCC, TCS, AHTN and HHCB in biosolid-amended soils

“…A previous study showed that TCS inhibited plant growth, with rice seeds being more sensitive than cucumber seeds with EC50 values of 57 and 108 mg/kg (Liu et al, 2009). The only terrestrial toxicity data for TCC was LC50 value (40 mg/kg) for the earthworms Eisenia fetida (Snyder et al, 2011), thus the calculated PNEC value for TCC was 40 μg/kg. Amorim et al (2010) reported the terrestrial toxicity data for TCS to various invertebrates and plants with the lowest EC10 value of 0.6 mg/kg (Eisenia andrei), and proposed the PNEC value of 60 μg/kg for TCS.…”

Distribution and accumulation of endocrine-disrupting chemicals and pharmaceuticals in wastewater irrigated soils in Hebei, China

“…Soil respiration was significantly inhibited by triclosan at concentrations more than 10 mg/kg during the first 4 days of incubation, but recovered later on after longer incubation . The only terrestrial toxicity data for triclocarban was LC50 value (40 mg/kg) for Eisenia fetida earthworms (Snyder et al, 2011), so the PNEC value for triclocarban was 40 mg/kg.…”

Nanomolar concentration of triclocarban increases the vulnerability of rat thymocytes to oxidative stress

“…Triclocarban has attracted some public attention because of reports that it acts as an endocrine disruptor (Chen et al, 2008;Giudice and Young, 2010). However, there is limited information concerning the cytotoxic actions of triclocarban in mammalian cells, although these actions have been examined, to some extent, in aquatic and terrestrial organisms (Lawrence et al, 2009;Snyder et al, 2011). Nanomolar concentrations of triclocarban were recently detected in human blood after the use of triclocarban-containing soap during showering (Schebb et al, 2012) and in rat blood after the topical application of triclocarban-containing cream (Schebb et al, 2011b).…”

“…It is present in surface waters and bioaccumulates in aquatic animals (Coogan and La Point, 2008;Zhao et al, 2010;Snyder et al, 2011;Schebb et al, 2011a). Triclocarban has attracted some public attention because of reports that it acts as an endocrine disruptor (Chen et al, 2008;Giudice and Young, 2010).…”