Toxicity and Bioaccumulation of Fipronil in the Nontarget Arthropodan Fauna Associated with Subalpine Mosquito Breeding Sites

Survival, Growth, and Body Residues of Hyalella azteca (Saussure) Exposed to Fipronil Contaminated Sediments from Non-Vegetated and Vegetated Microcosms

“…Few studies have examined the bioavailability of fipronil in crustaceans (Chaton et al 2002;Biever et al 2003;Smith et al 2007) and only Smith et al (2007) assessed any fipronil metabolites (fipronil-sulfone). These previous studies showed a broad spectrum of fipronil concentrations in crustacean tissues.…”

“…Smith et al (2007) showed fipronil and fipronilsulfone body residues ranging from \1 to 5 and 14 to 201 ng g -1 , respectively in H. azteca. Chaton et al (2002) noted that crustaceans appear to be able to accumulate large amounts of fipronil, regardless of their sensitivity to the compound and suggested that crustaceans may either be resistant to the compound's mode of action, able to detoxify the compound, or accumulate the compound in body fat or cuticle. In the current study, fipronil body residues as great as 78 ng g -1 elicited no observed survival or growth effects for H. azteca.…”

Evaluation of the risk of mixtures of paddy insecticides and their transformation products to aquatic organisms in the Sakura River, Japan

“…Acute toxicity data and risk quotients of insecticides and transformation products for Cheumatopsyche brevilineata and Daphnia magna TPs, for which D. magna is 300 times less sensitive than C. brevilineata. Chaton et al [32] reported that, in toxicological bioassays and bioaccumulation analyses, six nontarget aquatic arthropods showed different sensitivity levels to fipronil. Chironomus annularius, which bioaccumulated fipronil more than did Daphnia pulex, was much more sensitive to fipronil than D. pulex [32].…”

“…Chaton et al [32] reported that, in toxicological bioassays and bioaccumulation analyses, six nontarget aquatic arthropods showed different sensitivity levels to fipronil. Chironomus annularius, which bioaccumulated fipronil more than did Daphnia pulex, was much more sensitive to fipronil than D. pulex [32]. Although bioaccumulation analyses were not conducted in present study, the different sensitivity to fipronil and its TPs between C. brevilineata and D. magna might be due to the differences in their bioaccumulation, as with that of C. annularius and D. pulex studied by Chaton et al [32].…”

Citotoxicity of Fipronil on Hepatocytes Isolated from Rat and Effects of Its Biotransformation

“…Fipronil is an insecticide that is widely used to control various pests, such as cockroaches, mosquitoes, locusts, fleas, lice and ticks in the dogs, cats and cattle (Chaton et al 2002;Aajoud et al 2003). This insecticide belongs to the new generation of insecticides that have been developed to reduce the damage to the environment and mammals.…”