Toxicity of butene-fipronil, in comparison with seven other insecticides, in Leptinotarsa decemlineata and Drosophila melanogaster

Arain, Muhammad Shahid; Wan, Pin-Jun; Shakeel, Muhammad; Farooq, Muhammad; Hu, Xingxing; Shah, Syed Ali Haider; Elzaki, Mohammed Esmail Abdalla; Li, Guoqing

doi:10.1007/s12600-016-0560-z

Cited by 2 publications

(3 citation statements)

References 51 publications

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“…This inevitably leads to the development of resistance to various insecticides, such as organophosphates, carbamates, pyrethroids, and neonicotinoids. In addition, Drosophila melanogaster grows quickly and lays many eggs, which makes it as an excellent model system for assessing insecticide toxicities …”

Section: Materials and Methodsmentioning

confidence: 99%

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Quantitative Structure–Activity Relationship Modeling and Docking of Monoterpenes with Insecticidal Activity Against Reticulitermes chinensis Snyder and Drosophila melanogaster

Rodrigues

Maia

Muratov

et al. 2020

J. Agric. Food Chem.

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The goal of this study was to perform in silico identification of bioinsecticidal potential of 42 monoterpenes against Drosophila melanogaster and Reticulitermes chinensis Snyder. Quantitative structure−activity relationship (QSAR) modeling was performed for both organisms, while docking and molecular dynamics were used only for Drosophila melanogaster. Neryl acetate has the lowest interaction energy (−87 kcal/mol) against active site of acetylcholinesterase, which is comparable to the ones of methiocarb and pirimicarb (−90 kcal/mol) and reported PDB binder 9-(3-iodobenzylamino)-1,2,3,4-tetrahydroacridine (−112.67 kcal/mol). Interaction stability was verified by molecular dynamics simulations and showed that the stability of ACHE active site complexes with three selected terpenes is comparable to the one of the pirimicarb and methiocarb. Overall, our results suggest that pulegone, citronellal, carvacrol, linalyl acetate, neryl acetate, citronellyl acetate, and geranyl acetate may be considered as a potential pesticide candidates.

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Section: Materials and Methodsmentioning

confidence: 99%

“…In addition, Drosophila melanogaster grows quickly and lays many eggs, which makes it as an excellent model system for assessing insecticide toxicities. 12 2.3. Data Set Compilation and Curation.…”

Section: Methodsmentioning

confidence: 99%

Quantitative Structure–Activity Relationship Modeling and Docking of Monoterpenes with Insecticidal Activity Against Reticulitermes chinensis Snyder and Drosophila melanogaster

Rodrigues

Maia

Muratov

et al. 2020

J. Agric. Food Chem.

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“…L. decemlineata has been proposed as an important species for the development of predictive strategies to minimize the resistance to pesticides (Kitaev et al, 2017). This species is also a reference model in research, where resistance of two or more species is confronted (Arain et al, 2017; Spit et al, 2017).…”

Section: Agronomy and Ecologymentioning

confidence: 99%

Beetles as Model Organisms in Physiological, Biomedical and Environmental Studies – A Review

et al. 2019

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Model organisms are often used in biological, medical and environmental research. Among insects, Drosophila melanogaster, Galleria mellonella, Apis mellifera, Bombyx mori, Periplaneta americana , and Locusta migratoria are often used. However, new model organisms still appear. In recent years, an increasing number of insect species has been suggested as model organisms in life sciences research due to their worldwide distribution and environmental significance, the possibility of extrapolating research studies to vertebrates and the relatively low cost of rearing. Beetles are the largest insect order, with their representative – Tribolium castaneum – being the first species with a completely sequenced genome, and seem to be emerging as new potential candidates for model organisms in various studies. Apart from T. castaneum , additional species representing various Coleoptera families, such as Nicrophorus vespilloides, Leptinotarsa decemlineata, Coccinella septempunctata, Poecilus cupreus, Tenebrio molitor and many others, have been used. They are increasingly often included in two major research aspects: biomedical and environmental studies. Biomedical studies focus mainly on unraveling mechanisms of basic life processes, such as feeding, neurotransmission or activity of the immune system, as well as on elucidating the mechanism of different diseases (neurodegenerative, cardiovascular, metabolic, or immunological) using beetles as models. Furthermore, pharmacological bioassays for testing novel biologically active substances in beetles have also been developed. It should be emphasized that beetles are a source of compounds with potential antimicrobial and anticancer activity. Environmental-based studies focus mainly on the development and testing of new potential pesticides of both chemical and natural origin. Additionally, beetles are used as food or for their valuable supplements. Different beetle families are also used as bioindicators. Another important research area using beetles as models is behavioral ecology studies, for instance, parental care. In this paper, we review the current knowledge regarding beetles as model organisms and their practical application in various fields of life science.

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Toxicity of butene-fipronil, in comparison with seven other insecticides, in Leptinotarsa decemlineata and Drosophila melanogaster

Cited by 2 publications

References 51 publications

Quantitative Structure–Activity Relationship Modeling and Docking of Monoterpenes with Insecticidal Activity Against Reticulitermes chinensis Snyder and Drosophila melanogaster

Quantitative Structure–Activity Relationship Modeling and Docking of Monoterpenes with Insecticidal Activity Against Reticulitermes chinensis Snyder and Drosophila melanogaster

Beetles as Model Organisms in Physiological, Biomedical and Environmental Studies – A Review

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