Toxicity of Mixtures of Polychlorinated Dibenzo-p-dioxins, Dibenzofurans, and Biphenyls Determined by Dose-Response Curve Analysis

Li, W; Wu, Wenbo; Schramm, K.‐W.; Xu, Yiping; Kettrup, A.

doi:10.1007/s001289900909

Cited by 6 publications

(4 citation statements)

References 12 publications

(9 reference statements)

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“…For example, Li et al (1999) observed that effects of polyhalogenated aromatic hydrocarbon, 2,3,7,8-TCDD, combined with higher toxic compounds, lower toxic compounds, or even with inactive compounds, were significantly different from a single additive interaction. In an in vitro study, Kholkute and Dukelow (1997) found that a mixture of PCBs resulted in adverse effects on fertilization, oocytes, and 2-cell embryos in the mouse without additive or synergistic effects.…”

Section: Polycyclic Aromatic Hydrocarbons (Pahs)mentioning

confidence: 99%

Organochlorine, PCB, PAH, and metal concentrations in eggs of loggerhead sea turtles (Caretta caretta)from northwest Florida, USA

Alam

Brim²

2000

Journal of Environmental Science and Health, Part B

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Composite samples of unhatched and physically unaltered loggerhead sea turtle, Caretta caretta, eggs collected from 20 nests along northwest Florida were analyzed for organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), and metals. Chemical analyses revealed that turtle eggs contained detectable amounts of metals, PAHs, and PCBs. Only one OCP, p,p'-DDD, was detected, and its presence was restricted to eggs from two nesting sites. None of the PCB concentrations exceeded the Food and Drug Administration's (FDA) action limit. Concentrations of dioxin-like PCB congeners, 105, 118, and 126, and total PCBs were also detected and are contributors to the toxic burden of loggerhead sea turtle eggs. Concentrations of PAHs, 1,2,5,6-dibenzanthracene, 1-methyl naphthalene, C1-naphthalene and naphthalene were variable at nesting sites. Comparison of mean metal burdens in eggs from different beaches suggested that no uniform geographic gradients exist. Presence of OCPs, PCBs, PAHs and metals and their additive or synergistic toxicity is a concern to loggerhead sea turtle eggs; however, additive or synergistic impacts for loggerhead sea turtles are largely undocumented.

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Section: Polycyclic Aromatic Hydrocarbons (Pahs)mentioning

confidence: 99%

Organochlorine, PCB, PAH, and metal concentrations in eggs of loggerhead sea turtles (Caretta caretta)from northwest Florida, USA

Alam

Brim²

2000

Journal of Environmental Science and Health, Part B

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show abstract

“…Polychlorinayed dibenzo-p-dioxins and dibenzofurans (PCDD/F) have been globally distributed and can be found in all environmental media (Somogyi, 1997;Li et al, 1999). They are chemically stable, have low solubilities in water, and have been shown to be accumulated in the foodweb (Geyer et al, 1990;Bonn, 1998;Landi et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Persistence of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F) in Ya-Er Lake area, China

Schramm

et al. 2001

Environment International

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“…Many studies are underway to determine the e!ects of exposure to PCDD/F on human health (Somogyi, 1997(Somogyi, /1998Landi et al, 1998;Li et al, 1999). Organisms may accumulate chemical substances either directly from the surrounding environment or from their diet.…”

Section: Introductionmentioning

confidence: 99%

Distribution, Transformation, and Long-Term Accumulation of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans in Different Tissues of Fish and Piscivorous Birds

Zhang

Schramm

et al. 2000

Ecotoxicology and Environmental Safety

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Toxicity of Mixtures of Polychlorinated Dibenzo-p-dioxins, Dibenzofurans, and Biphenyls Determined by Dose-Response Curve Analysis

Cited by 6 publications

References 12 publications

Organochlorine, PCB, PAH, and metal concentrations in eggs of loggerhead sea turtles (Caretta caretta)from northwest Florida, USA

Organochlorine, PCB, PAH, and metal concentrations in eggs of loggerhead sea turtles (Caretta caretta)from northwest Florida, USA

Persistence of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F) in Ya-Er Lake area, China

Distribution, Transformation, and Long-Term Accumulation of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans in Different Tissues of Fish and Piscivorous Birds

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