Toxicokinetics of carbofuran in house fly, Musca domestica L

Collins, C.; Kennedy, J.M.; Miller, Thomas A.

doi:10.1016/0048-3575(83)90118-9

Cited by 4 publications

(3 citation statements)

References 16 publications

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“…Biphasic phenomena have been also reported in the penetration of various insecticides. 16,17) Acetone in which 2 was dissolved may work as a carrier to produce the first steep phase. Alternatively, there might be a saturable pool which absorbs a definite amount of chemicals rapidly in the integument, and then releases them inside the body.…”

Section: Discussionmentioning

confidence: 99%

Penetration and Metabolism of Bicyclic Phosphorus Esters Which Affect Their Insecticidal Activity against the Housefly

Ozoe¹,

Karino²,

Mochida³

et al. 1986

J. Pestic. Sci.

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Pretreatmentwith the microsomal oxidase inhibitor piperonyl butoxide (pb) greatly improved the topical insecticidal activity of the GABA antagonist, 4-n-propyl-2,6,7-trioxa-lphosphabicyclo[2.2.2]octane 1-oxide (4-n-propyl BP),* against the housefly, Musca domestica L., when the synergistic ratio was 313. The insecticidal activity was also enhanced by bypassing the integument with injection without pb pretreatment.When tested by four different methods, the order of the 24-hr LD50 values (ug/fly) for 4-n-propyl BP was: injection, pretreated with pb (0.169)

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Section: Discussionmentioning

confidence: 99%

Penetration and Metabolism of Bicyclic Phosphorus Esters Which Affect Their Insecticidal Activity against the Housefly

Ozoe¹,

Karino²,

Mochida³

et al. 1986

J. Pestic. Sci.

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show abstract

“…Because the enzyme kinetics were not studied in the present experiment, saturation of hydrolytic enzyme at the higher dose was uncertain. Possible saturation kinetics at a higher dose has been reported in house flies treated with carbofuran (Collins et al, 1983), methyl parathion, and…”

Section: <T T Max Timementioning

confidence: 87%

“…The rate of transformation, how ever, was slower than at the LD^g dosages. Low radioactivity recovered from unextractable residue implies that few compounds bind to tissues Collins et al (1983). compared toxicokinetics of carbofuran in house flies at an LDgQ dose and an LD^q dose.…”

mentioning

confidence: 99%