Toxicological Assessment of Arsenic-Induced Hematological Alterations and Chromosomal Aberrations in Tilapia<i>Oreochromis mossambicus</i>

Fish tilapia Oreochromis mossambicus were collected from a contaminated Seri Serdang (SS) pond potentially receiving domestic effluents and an uncontaminated pond from Universiti Putra Malaysia (UPM). The fish were dissected into four parts namely gills, muscles, intestines, and liver. All the fish parts were pooled and analyzed for the concentrations of Cd, Cu, Fe, Ni, Pb, and Zn. Generally, the concentrations of all metals were low in the edible muscle in comparison to the other parts of the fish. It was found that the levels of all the heavy metals in the different parts of fish collected from the SS were significantly (P<0.05) higher than those from UPM, indicating greater metal bioavailabilities in the SS pond. The sediment data also showed a similar pattern with significantly (P<0.05) higher metal concentrations in SS than in UPM, indicating higher metal contamination in SS. Potential health risk assessments based on provisional tolerable weekly intake (PTWI) and the amount of fish required to reach the PTWI values, estimated daily intake (EDI), and target hazard quotient (THQ) indicated that health risks associated with heavy metal exposure via consumption of the fish's muscles were insignificant to human. Therefore, the consumption of the edible muscles of tilapia from both ponds should pose no toxicological risk of heavy metals since their levels are also below the recommended safety guidelines. While it is advisable to discard the livers, gills, and intestines of the two tilapia fish populations before consumption, there were no potential human health risks of heavy metals to the consumers on the fish muscle part.

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Pollution and health risk assessment of heavy metals in soils of Guizhou, China

Gao

Fen

Zhang³

et al. 2021

Ecosyst Health Sustain

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Mining of minerals in Guizhou, China, where it is enriched with reserves, may lead to soil contamination with heavy metals. We assessed the risk of eight typical heavy metals in Guizhou soils by collecting province-wide data available in the literature and using the geo-accumulation index method, the ecological risk assessment method, and the USEPA health risk assessment model. The concentrations of eight heavy metals, except for Pb and Cr, were above the background levels. Soil heavy metal pollution evaluation results showed that As, Cu, Zn, Pb, Cr, Cd, and Ni reached the pollution levels, while Hg fell into the category of moderate contamination. As, Cu, Zn, Pb, Cr, and Ni posed low potential ecological risk, while Cd and Hg demonstrated a considerable or a very high potential ecological risk. Totally, the integrated potential ecological risk was ranked “very high” . Regarding to health risk, the non-carcinogenic risks caused by heavy metals were insigniﬁcant, but the carcinogenic risk caused by As was signiﬁcant. Consequently, there appeared serious soil contamination of Hg and As, with the latter also being the greatest potential risk to human health. Both Hg and As should stay at the highest priory for remediation efforts in Guizhou soils.

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Toxicological Assessment of Arsenic-Induced Hematological Alterations and Chromosomal Aberrations in TilapiaOreochromis mossambicus

Cited by 3 publications

References 31 publications

Genotoxicity Biomarkers for Environmental Health Assessment Towards Sustainable Management of Fish Genetic Resources

Genotoxicity Biomarkers for Environmental Health Assessment Towards Sustainable Management of Fish Genetic Resources

Potential human health risk assessment of heavy metals via the consumption of tilapia Oreochromis mossambicus collected from contaminated and uncontaminated ponds

Pollution and health risk assessment of heavy metals in soils of Guizhou, China

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