Toxicological effects and oxidative stress responses in freshwater snail, Lanistes carinatus, following exposure to chlorpyrifos

Khalil, Abdelmonem M.

doi:10.1016/j.ecoenv.2015.03.010

Cited by 53 publications

(19 citation statements)

References 36 publications

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“…The results observed in the present study imply that probably in the metabolism of chlorpryifos in the freshwater snails H. duryi, ROS were indeed produced and probably that caused the defense mechanism of the snails to be activated (indicated by activation of CAT, GPX and GST) probably as an adaptive mechanism to overcome the oxidative stress induced effects of chlorpyrifos. Our results are supported by Khalil [32] who also reported induction of CAT, GPX and GST in the freshwater snail Lanistes carinatus exposed to the organophosphorus insecticide chlorpyrifos.…”

Section: Discussionsupporting

confidence: 81%

Pollutants, Snails, Oxidative-Stress, Organophosphates, Metals

Basopo¹,

Ngabaza²

2015

ABC

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Aquatic reservoirs remain the ultimate sink of chemical pollutants emanating from anthropogenic activities such as agriculture, mining and industry. Freshwater biota undoubtedly is at risk from the adverse effects of these water pollutants and there is therefore, a need to monitor effects of these chemical pollutants in order to safeguard the health of aquatic biota. We investigated the oxidative stress effects of chlorpyrifos and lead on the freshwater snail Helisoma duryi to assess the potential of using this enzyme system as a biondicator of exposure to environmental pollutants. Groups of snails were exposed to 5 ppb lead acetate and 25 ppb chlorpyrifos for 7 days after which half of the snails were sacrificed and the other half were allowed to recover in clean water and sacrificed after another 7 days. Post mitochondrial fractions were used to measure the activities of the following antioxidant enzymes: superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase and diphosphotriphosphodiaphorase. Both pollutants enhanced the activities of all the antioxidant enzymes suggesting a defensive mechanism by the snail to combat the oxidative stress due to the organophosphate chlopryrifos and metal pollutant lead. There was a significant recovery of the antioxidant defense system of the snails allowed to recover in clean water shown by the reduced alteration of the antioxidant enzyme activities of the snails allowed to recover for 7 days. This suggests the need to minimize exposure of aquatic biota to chemical pollutants and remediate the polluted water reservoirs in order to safeguard the health of aquatic life.

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Section: Discussionsupporting

confidence: 81%

Pollutants, Snails, Oxidative-Stress, Organophosphates, Metals

Basopo¹,

Ngabaza²

2015

ABC

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“…They indirectly protect cells against the adverse effects of xenobiotics, carcinogens and toxic radicals (Griffith, 1999). Lipid peroxidation has been suggested to play a role in metal toxicity, with numerous studies undertaken using malondialdehyde (MDA) as biomarker of oxidative stress (Steven and Nerishi, 1992;Khalil, 2015 andOgunka-Nnoka et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

Physa acuta snail as a biomonitor for the efficacy of bioremediation treatment of heavy metals (Fe III and Cd II) using the fungus (Eupenicillium lapidosum) in lined and unlined laboratory conditions

Osman¹,

Mohamed²,

Kader³

et al. 2018

Egypt. J. of Aquatic Biolo. and Fish.

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“…After 96 h exposure, shrimps of each experimental tank were collected, and brain, hepatopancreas, gills, and muscles were dissected, cleaned and immediately washed with ice-cold saline. Samples were weighed and homogenized in ice-cold Potassium Phosphate Buffer (50mM, pH 7.5, EDTA 60mM) [25] containing protease inhibitor (Sigma P2714) by using a glass homogenizer. Then, the homogenate was centrifuged at 3600 rpm for 15 min at 4˚C [KUBOTA (3700), Japan] and the supernatant corresponding to the post-mitochondrial fraction was used to evaluate enzymatic (CAT, GR, GST) and lipid peroxidation levels (LPO).…”

Section: Tissue Preparation For Antioxidant Enzymes Assaysmentioning

confidence: 99%

“…chlorpyrifos [60][61][62]. The observed LPO resulting from exposure to chlorpyrifos may lead to cell death [25]. Hence, L vannamei can be used as a test organism for in situ assessment of lipid oxidation.…”

Section: Plos Onementioning

confidence: 99%

Effects of chlorpyrifos on the crustacean Litopenaeus vannamei

2020

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Shrimps can be used as indicators of the quality of aquatic systems exposed to a variety of pollutants. Chlorpyrifos is one of the most common pesticides found in environmental samples. In order to evaluate the effects of chlorpyrifos, adult organisms of Litopenaeus vannamei were exposed to two sublethal concentrations of the pesticide (0.7 and 1.3 μg/L) for four days. The LC 50 (96-hours) value was determined and Lipid oxidation levels (LPO) and the activities of catalase (CAT), glutathion peroxidase (GPx), glutathion-S-transferase (GST) were assessed on the muscle, hepatopancreas and gills from the exposed organisms. In addition, inhibition of acetylcholinesterase (AChE) was determined in the brain. LC 50 (96hours) was 2.10 μg/L of chlorpyrifos. Catalase activity and LPO were elevated in the three tissues, whereas a decrease of AChE activities in the brain and an increase of GST activity in the hepatopancreas were observed.

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Toxicological effects and oxidative stress responses in freshwater snail, Lanistes carinatus, following exposure to chlorpyrifos

Cited by 53 publications

References 36 publications

Pollutants, Snails, Oxidative-Stress, Organophosphates, Metals

Pollutants, Snails, Oxidative-Stress, Organophosphates, Metals

Physa acuta snail as a biomonitor for the efficacy of bioremediation treatment of heavy metals (Fe III and Cd II) using the fungus (Eupenicillium lapidosum) in lined and unlined laboratory conditions

Effects of chlorpyrifos on the crustacean Litopenaeus vannamei

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