Toxicological effects of inorganic nanoparticles on human lung cancer A549 cells

Proteomics-based safety evaluation of multi-walled carbon nanotubes

“…This residual iron may cause cytotoxicity accompanied by a positive reaction with trypan blue. Choi et al (2009) reported that iron oxide caused cell death associated with membrane damage, which is consistent with our result that no cells exposed to HTT2800 were stained by trypan blue.…”

Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells

“…1,9,26,[40][41][42][43][44] Figure 1 shows a comparison of the kinetics of uptake of silica nanoparticles in A549 cells in serum free and complete media, obtained by flow cytometry, as described in the Methods. As anticipated in Supplementary Figure S1, the kinetic study also clearly indicated that uptake was always higher when the nanoparticles were exposed to cells in SF.…”

Reactive‐Oxygen‐Species‐Responsive Drug Delivery Systems: Promises and Challenges

“…In addition, the pore‐surface biphasic structure of MSN allows not only to load various hydrophobic agents into their uniform mesoporous channel, but also to develop versatile drug delivery systems by endowing various functions including diagnosis, stimuli‐responsiveness and targeting ability to the delivery systems. In particular, MSNs are known to induce the ROS generation in several cell lines, which show their potential in the development of ROS‐responsive drug delivery systems 74, 75, 76, 77, 78, 79, 80. Therefore, in this section, we would like to discuss the MSN‐based ROS‐responsive drug delivery systems.…”