“…2012).It grows mostly in shady and humid areas at altitudes of 3,300–3,900 m ( Jan et al., 2017 ; Grauso et al., 2020 ; Srutek and Teckelmann, 1998 ; Liu and Sun, 2005 ; Maričić et al., 2021 ). Stems and leaves of U. dioica are nutrient rich containing large amount of protein and a variety of essential amino acids, which make it as a useful choice for food and herbal treatments ( Singh and Sharma, 2011 ). Furthermore, it has a variety of active ingredients, i.e., U. dioica lectins, polysaccharide, and flavonoids, which can produce antioxidant and anticancer effects at certain concentrations by promoting apoptosis of cancer cells and enhancing expression of pro-apoptotic proteins to exert anti-tumor effects ( Wang and Pantopoulos, 2011 ; Abdeltawab et al., 2012 ; Said et al., 2015 ).…”