Toxopathological Study of Methamyl Effect on the Rock Pigeons (Culumba Livia Gaddi)

Abstract

This Study was conducted in animal house in Faculty of veterinary medicine of university of kufa. This study was designated to assess the neuropathy of Organophosphorus pesticide (Methomyl) after long-term administration of low dose in Rock pigeons. The Clinical signs, gross lesions and histopathological assessment of nervous tissue were described. A total of 20 pigeons, 3months old and about 500g average body weight pigeons were used in this study. The pigeons were equally divided in to tow groups. The dose was calculated based on study at close pilot at 0.02 ml and gradually lose the dose down to the toxic non-lethal dose. The toxic dose was 0.01 ml. One group was daily administered via oral gavages with 0.01 ml of methomyl; for 21 days where as the other group were leave control without administration. Organophosphorus pesticide treated groups exhibited both muscarinic and nicotinic signs of toxicity.