“…After the infection was confirmed and before treatment onset, we determined the levels of specific anti-T. gondii IgG1, IgG2, IgG3, and IgG4 antibodies and proliferation in vitro of peripheral blood mononuclear-specific cells and their cytokine production (19). Congenitally infected newborns were evaluated at 1-year follow-up, and their clinical features classified according to the location (neurological or disseminated) and severity (mild or moderate/severe) (9). In brief, local infection refers to patients with neurological, ophthalmic, or both alterations, such as intracranial calcifications, hydrocephalus, microcephalus, retinochoroiditis, uveitis, and intraocular hemorrhage.…”