Trace element abnormalities in the scalp hair of breast cancer patients

Kabiri, Zeynab; Kakuee, O.; Fathollahi, V.; Stout, Brittany

doi:10.1142/s0129083514500065

Cited by 3 publications

(3 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The same trend was also given by various workers with different methods and techniques [30,37,59,60]. Higher Ca levels are found in the scalp hair and blood of breast cancer patients using PIXE and WDXRF in [32,39]. Cationic calcium homeostasis in the plasma is tightly maintained through absorption, excretion and secretion and storage in bone.…”

Section: Role Of Trace Elementsmentioning

confidence: 53%

“…In the past, various researchers have reported a high level of iron in human breast cancer tissues as compared to the normal one [27][28][29][30][35][36][37][38]. Elevated iron levels are also reported in in blood [32,34] and scalp hair [39] of breast cancer patients using PIXE and WDXRF. Iron (Fe) plays a vital role in the human body and is an essential element.…”

Section: Role Of Trace Elementsmentioning

confidence: 99%

“…Studies [27,29,30,37,38] using various techniques are in well agreement with past results. Many studies showed that the level of Cu and in blood serum [32,34] and in hairs [39] of breast cancer patients are higher as compared to the normal one. The daily requirement of Cu intake is about 2 mg/day and heavy dose ingestion causes various diseases.…”

Section: Role Of Trace Elementsmentioning

confidence: 99%

See 2 more Smart Citations

Role of Trace Elements in Breast Cancer and Their Characterization Using X-Ray Fluorescence Techniques

Kainth¹,

Khandelwal²,

Singh³

et al. 2021

Trace Elements and Their Effects on Human Health and Diseases

View full text Add to dashboard Cite

Breast cancer is the most common serious disease that occurs in the human body. Trace elements have an important function in biological and metabolism processes including activation or inhibition of enzymatic reaction, reactive oxygen species (ROS), competition between trace elements and metal proteins for binding positions and modifications in the permeability of cellular membranes which influence carcinogenic processes. A significant association between the abnormal concentration of trace elements and breast cancer has been found in many studies using XRF techniques like energy dispersive X-ray fluorescence (EDXRF), particle induced X-ray emission (PIXE), total reflection X-ray fluorescence (TXRF), wavelength dispersive X-ray fluorescence (WDXRF) and synchrotron induced X-ray fluorescence (SRIXE). This chapter considers trace elements like Fe, Cu, Zn, Cr, Cl, Ca, P, S, K, Na, Mg, Se, As and Sr. from the standpoint of their role as either inhibitory or causative agents of breast cancer. XRF techniques and sample preparation methods for analysis of biological samples are also reviewed.

show abstract

Section: Role Of Trace Elementsmentioning

confidence: 53%

Section: Role Of Trace Elementsmentioning

confidence: 99%

Section: Role Of Trace Elementsmentioning

confidence: 99%

See 1 more Smart Citation

Role of Trace Elements in Breast Cancer and Their Characterization Using X-Ray Fluorescence Techniques

Kainth¹,

Khandelwal²,

Singh³

et al. 2021

Trace Elements and Their Effects on Human Health and Diseases

View full text Add to dashboard Cite

show abstract

Sex-specific differences in elemental movement from blood to hair

et al. 2018

View full text Add to dashboard Cite

We investigated the relationships between the element concentrations in blood and hair to clarify the sex-specific differences in elemental movement from blood to hair, as we confirmed the presence of large sex-specific differences in the concentrations of certain elements in hair in our previous study. First, we compared the elemental concentrations in serum/plasma taken from healthy people ([Formula: see text] females, 142 males) and found that there were significant differences (up to 20%) between females and males in levels of phosphorus, sulfur, calcium, bromine, and lead. We then examined the sex-specific differences in the elemental transfer factors from blood to hair by analyzing plasma and hair samples that had been simultaneously collected from the same people (20 females, 21 males). Calcium and selenium showed significant differences in transfer factors from plasma to hair. Particularly, large sex-specific differences in the calcium concentration were explained by the difference in the transfer factors from blood to hair. We also examined the sex-specific differences among teenaged subjects alone ([Formula: see text] females, 9 males; average age was approximately 17 years old) and noted no significant difference in the transfer factors between sexes. Taken together, these findings indicate that the transfer factors themselves are influenced by the excretion of sex hormones.

show abstract

Long-term and season-specific changes in the body concentrations of iron, copper, zinc, and selenium by means of quantitative analyses of beard samples collected every day — A case study

et al. 2019

View full text Add to dashboard Cite

A total of 4269 beard samples were collected from the same person every day over a 12-year period and analyzed by PIXE using a standard-free method. It was found that the concentrations of copper and zinc showed certain short-term changes but did not show a noticeable long-term trend over the study period, with only iron showing a slightly decreasing tendency with age. All of these elements showed clear yearly variations with a cycle of a few years possibly due to periodic metabolic changes in the subject’s body or long-term changes in eating habits. In contrast, however, selenium showed clear seasonal variations. Its concentration significantly increased in the summer and decreased in the winter, just as was observed with arsenic and mercury. This suggests that most of the subject’s selenium intake was from marine products, whose supply and consumption were increased in the summer. These findings confirmed that beard analyses are useful not only for evaluating essential-element intake but also for estimating the relationship between the body-element concentrations and ingestion of certain foods.

show abstract

Trace element abnormalities in the scalp hair of breast cancer patients

Cited by 3 publications

References 49 publications

Role of Trace Elements in Breast Cancer and Their Characterization Using X-Ray Fluorescence Techniques

Role of Trace Elements in Breast Cancer and Their Characterization Using X-Ray Fluorescence Techniques

Sex-specific differences in elemental movement from blood to hair

Long-term and season-specific changes in the body concentrations of iron, copper, zinc, and selenium by means of quantitative analyses of beard samples collected every day — A case study

Contact Info

Product

Resources

About