Tracheo-bronchitis Associated with Crohn's Disease Improved on Inhaled Corticotherapy

Abstract

We report a case of tracheo-bronchitis in Crohn's disease. A 23-year-old Japanese woman who had been diagnosed with Crohn's disease three years previously was hospitalized. She had been suffering from dry cough for one month.

Tracheal Involvement in Crohn Disease: the First Case in Korea

“…Tracheobronchial involvement of CD is rare, although several cases have been reported [ 1 , 2 , 5 , 6 , 8 , 9 , 11 - 13 ]. Similar to previous reports [ 2 , 6 , 9 , 13 , 14 ] and to the colonoscopic findings for CD, the bronchoscopic findings in our case were mucosal irregularity, elevation, edema, and the presence of a yellowish patch-like lesion. In the present case, as in previous cases, the pathologic findings of the bronchial biopsy were epithelial and subepithelial infiltrates of diverse types of inflammatory cells including neutrophils, macrophages, lymphocytes, and plasma cells [ 2 , 6 , 9 , 13 , 14 ].…”

“…Similar to previous reports [ 2 , 6 , 9 , 13 , 14 ] and to the colonoscopic findings for CD, the bronchoscopic findings in our case were mucosal irregularity, elevation, edema, and the presence of a yellowish patch-like lesion. In the present case, as in previous cases, the pathologic findings of the bronchial biopsy were epithelial and subepithelial infiltrates of diverse types of inflammatory cells including neutrophils, macrophages, lymphocytes, and plasma cells [ 2 , 6 , 9 , 13 , 14 ]. According to Asami et al [ 3 ], bronchoscopic and pathologic findings such as these indicate that tracheobronchial inflammation results from the activation of macrophages and T lymphocytes, as does colonic inflammation.…”

Wheezes, blisters, bumps and runs: multisystem manifestations of a Crohn's disease flare-up

“…Tracheobronchial stenosis has been reported in patients with Crohn's disease, [1][2][3][4][5] and pyoderma gangrenosum in association with tracheobronchitis has been documented in a patient without inflammatory bowel disease. 6 However, this case is distinctive in that respiratory, dermatologic, rheumatologic and gastrointestinal manifestations followed a parallel clinical course.…”

Tracheitis – A Rare Extra-Intestinal Manifestation of Ulcerative Colitis in Children

“…In refractory cases procedures like laser beam, balloon dilatation, stent placement or tracheotomy may be necessary to maintain patent airway. 10 , 11 , 12 , 13 , 20 , 21 , 22 , 23 , 24 According to our experience, in the first case the girl had evolution to respiratory failure in spite of inhaled corticosteroid therapy. This highlights the fact that inhaled administration may not be efficient enough in severe cases.…”