Traditional Chinese medicine: herb-drug interactions with aspirin

Abstract

Traditional Chinese medicine (TCM)-based herbal therapies have gained increasing popularity worldwide, raising concerns of its efficacy, safety profile and potential interactions with Western medications. Antithrombotic agents are among the most common prescription drugs involved in herb-drug interactions, and this article focused on aspirin, one of the most widely used antiplatelet agents worldwide. We discussed herbs that have potential interactions by exploring Western and TCM approaches to thrombotic events. Common TCM indications for these herbs were also highlighted, including possible scenarios of their concurrent usage with aspirin. With greater awareness and understanding of potential herb-drug interactions, TCM and Western physicians may collaborate more closely to identify, treat and, most importantly, prevent adverse drug events.

Acute adrenal failure: a potentially fatal consequence of an adulterated herbal remedy

“…Concerns, therefore, have been raised regarding the efficacy, safety and monitoring of the manufacture of herbal remedies,1 3 19 and their frank adulteration 6–12. Furthermore, potential herb–drug interactions should be considered when prescribing conventional medications 3 20–23…”

Interakcje wybranych leków kardiologicznych ze składnikami diety

“…Żeń-szeń wykazuje działanie przeciwzakrzepowe w wyniku hamowania kilku etapów szlaku agregacji płytek krwi -potwierdzono to w badaniach klinicznych. Z tego względu warto zwrócić uwagę na stosowanie przez pacjentów suplementów zawierających żeń-szeń przy jednoczesnym stosowaniu leków przeciwpłytkowych, jednak według badań klinicznych ryzyko to jest niewielkie [15].…”

Potential Therapeutic Benefits of Herbs and Supplements in Patients with NAFLD

“…The lack of regulation in this field of treatment agents suggests caution with use of herbs in the context of NAFLD. Also, the lack of research indicates the possibility of drug interactions or adverse effects [ 158 , 159 , 160 , 161 ]. Herb–drug interactions have already been noted in warfarin, aspirin, alkylating agents, and cyclosporine, leading to toxicity in patients [ 158 , 161 ].…”

“…Also, the lack of research indicates the possibility of drug interactions or adverse effects [ 158 , 159 , 160 , 161 ]. Herb–drug interactions have already been noted in warfarin, aspirin, alkylating agents, and cyclosporine, leading to toxicity in patients [ 158 , 161 ]. Furthermore, as natural herbs are converted to supplements, the final product may no longer be purely herbal and can contain trace metals that could become toxic if taken consistently at high levels [ 162 ].…”