Traditional medicinal plants of cold desert Ladakh—Used against kidney and urinary disorders

Ballabh, Basant; Chaurasia, O. P.; Ahmed, Zakwan; Singh, Shashi Bala

doi:10.1016/j.jep.2008.04.022

Cited by 210 publications

(93 citation statements)

References 3 publications

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“…The results of ethnopharmacological investigations of local hakeems and healers show that the plants of the genus Perovskia are used as antiinflammatory, fortifier, antiseptic, leishmaniasis, anthelmintic, antimalarial, and for rheumatic pains (Ballabh et al, 2008;Esmaeili et al, 2008;Baquar, 1989;Hosseinzadeh & Amel, 2001;Moallem & Niapour, 2008;Nassiri et al, 2002). Previous phytochmical investigation on the plant Perovskia atriplicifolia showed phenolic and flavonoidal constituents (Perveen & Malik, 2006.…”

Section: Introductionmentioning

confidence: 99%

Anti-inflammatory constituents fromPerovskia atriplicifolia

Ahmad

Waheed

Tahir

et al. 2015

Pharmaceutical Biology

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Context: Perovskia atriplicifolia Benth (Labiantae) has long been used as a traditional herbal medicine for anti-inflammation in Pakistan; this prompted us to isolate anti-inflammatory compounds from this plant. Objective: The objective of this study was to isolate and characterize the anti-inflammatory principles from Perovskia atriplicifolia. Materials and methods: The CHCl 3 -soluble fraction of the methanol extract of the whole plant on column chromatography yielded compounds 1-6. The anti-inflammatory potential of the compounds 1-6 was evaluated by Leukotriene C4 (LTC 4 ) Release Assay which was performed according to the established protocol. LTC 4 in the supernatant of each well was measured using an ELISA kit (Cayman Chemical Co., Ann Arbor, MI). Results: The bioassay-guided phytochemical investigation of the CHCl 3 soluble fraction of the methanol extract of Perovskia atriplicifolia furnished six compounds, abrotanone (1), abrotandiol (2), (+)-pinoresinol (3), (+)-syringaresinol (4), (+)-lariciresinol (5), and (+)-taxiresinol (6). The compounds (1-6) were evaluated for their inhibitory activities on LTC 4 release. Among the tested compounds, (+)-taxiresinol (6) exhibited the most potent inhibition of LTC 4 release with an IC 50 value of 3.4 ± 0.09 mM followed by compounds 4, 5, 3, and 2 with an IC 50 value ranging from 7.9 ± 0.04 to 17.2 ± 0.07 mM. Abrotanone (1) showed the lowest inhibition of LTC 4 release with an IC 50 value of 35.1 ± 0.05 mM (the positive control, zileuton, 0.77 ± 0.05 mM). Conclusion: Compounds 1-6 were found to possess inhibitory activity and seem to have potential therapeutic effect on inflammatory diseases.

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Section: Introductionmentioning

confidence: 99%

Anti-inflammatory constituents fromPerovskia atriplicifolia

Ahmad

Waheed

Tahir

et al. 2015

Pharmaceutical Biology

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“…Polygonatum verticillatum is a perennial rhizomatous herb [42] from which fresh rhizomes syrup is employed valued against pain, stinging sensation, fever and tuberculosis [43]. This herb has also a diuretic effect along with reducing burning sensation during urinating when it is combined with other herbs [44]. Khan [45,46].…”

Section: Plants and Painmentioning

confidence: 99%

“…raw methanolic extract of rhizomes -analgesic effect on animal models [42] diuretic effect -statistically insignificant [42] Fresh rhizomes syrup -against pain, stinging sensation, fever, tuberculosis [43]; diuretic effect, reducing burning sensation during urinating when combined with other herbs [44] Remirea maritime (Cyperaceae) aqueous extract -analgesic proprieties in different experimental pain models [64] plant extract -antimicrobial, anti-inflammatory proprieties [128,129].…”

Section: Phyllanthus Fraternus (Euphorbiaceae)mentioning

confidence: 99%

Phytotherapeutical implications in pain perception - focusing on schizophrenia

Antioch¹,

Ciobîcă²,

Compaore³

et al. 2017

ijpm

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A b s t r a c tSc varying from abolition to lack of any kind of changes compared to normal controls and even hypersensitivity. In this way, the hypothesis of amending schizophrenia enhanced the importance of pain medication. But managing pain phenomenon in schizophrenia has large and unknown implications. Nevertheless, pharmacological interactions between the medications for these two entities are unknown and mos side option. ancient knowledge and current scientific pr To our best of knowledge, this is the first time when pain, plants and schizophrenia are discussed together. In this way, it seems that by replacing fully synthesized chemical products, the risk of side have curing effects on the psychotic activities in schizophrenia. Therefore, through this mini ethonopharmacological approaches in pain conditions in the context of schizop highlighted some cases of inappropriate usage of plants in traditional therapy.

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“…Ballabh & Chaurasia (2007) assessed and documented the new information on medicinal plants used for the treatment of cold, cough and fever by the traditional Amchis of Ladakh. Further, Ballabh et al (2008) document new ethno-medico-botanical information and traditional use of medicinal plants against kidney and urinary disorders, and thus aimed to conserve the rapidly disappearing traditional knowledge system of the amchis of Ladakh.…”

Section: Ethnomedicinal Plants Of Northern Indiamentioning

confidence: 99%