Traditional Neuroma Management

Starr, Brian; Chung, Kevin C.

doi:10.1016/j.hcl.2021.04.002

Cited by 20 publications

(34 citation statements)

References 68 publications

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“…A traumatic neuroma is typically associated with either a prior amputation (and has been referred to as a terminal neuroma) or an acute injury to the peripheral nerve [4][5][6][7][8][9]. However, a traumatic neuroma can develop from chronic and repetitive friction to a non-dissected nerve [10,16].…”

Section: Discussionmentioning

confidence: 99%

“…However, a traumatic neuroma can develop from chronic and repetitive friction to a non-dissected nerve [10,16]. These have been referred to as either a spindle neuroma or a neuroma-in-continuity [5,6,9,10].…”

Section: Discussionmentioning

confidence: 99%

“…Most traumatic neuromas are asymptomatic and occur post-amputation on the lower extremity [4][5][6]11]. However, when symptoms occur, the tumor can drastically alter the quality of the patient's life [4,8,9]. In addition to pain, a traumatic neuroma can produce cold intolerance, electrical sensitivity, numbness, and/or paresthesia [5,7,9,11].…”

Section: Discussionmentioning

confidence: 99%

“…A traumatic neuroma is a variant of the tumor that usually develops following injury to the nerve [4][5][6][7][8][9]. They are frequently located at an amputation site, or on an acral area of an extremity (such as the digit of the hand), or on the plantar surface of the toes (such as a Morton's neuroma) [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

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Tender Nasal Traumatic (TNT) Neuroma: Case Report and Review

Cohen¹,

Calame²

2022

Cureus

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A traumatic neuroma occurs at the injury site of a peripheral nerve; however, albeit rarely, this variant of a neuroma can involve a nerve that has not experienced penetrating trauma. A lower extremity amputation stump is the most common location of a traumatic neuroma. Traumatic neuromas may be symptomatic; tumor-associated pain can be severe and significantly affect the patient's quality of life. Several hypotheses have been postulated for the pathogenesis of neuroma-related pain, including alpha-smooth muscle actin, neural fiber structural changes, nerve growth factor, and/or sensitization of the affected nerve. In addition to prevention, non-surgical treatment (such as chemical interventions, cryotherapy, neuromodulation, pharmacologic agents, and physiotherapy) and surgical interventions (such as direct nerve repair at the time of injury or ligation of the nerve proximal to the neuroma and various potential methods to minimize subsequent irritation of the distal free end of the proximal nerve) have been used to manage neuromaassociated pain. A traumatic neuroma of the nose is rare. Indeed, it has only been described in three individuals: two women (including the Caucasian woman in this report and a Turkish woman) and one man. The benign tumor was extremely painful in both women; however, the man's lesion was non-tender. Prior trauma to the nasal site included either a laceration or elective surgery; however, the reported woman did not experience any penetrating trauma to her nose. The diagnosis was established following an excisional (for the man), incisional (for the Turkish woman), or punch (for the Caucasian woman) biopsy. Follow-up was provided for two of the patients. The man's neuroma had been completely excised, and he never developed tumor-associated tenderness. However, the pain persisted after the biopsy healed for the reported woman whose neuroma was not entirely removed. The explosive and markedly severe character of the reported patient's lesion-related tenderness prompted us to propose an acronym for this uncommon yet exquisitely painful variant of a neuroma: tender nasal traumatic (TNT) neuroma.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Tender Nasal Traumatic (TNT) Neuroma: Case Report and Review

Cohen¹,

Calame²

2022

Cureus

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“…This may be related to the formation of intercostal and intercostal cutaneous neuroma. Neuroma is formed when the peripheral nerve is damaged and cannot heal normally during operation [50]. The two main types of neuromas include end-stage neuromas that occur when the nerve is completely severed, or continuous neuromas with intact nerves [51].…”

Section: Intraoperative Factorsmentioning

confidence: 99%