A novel slow-release nitrogen fertilizer with high-water absorbency (SRNFWA) was prepared by cross-linking poly (acrylic acid-acrylic amide)/bentonite and urea. The synthesis conditions were studied systematically and optimized by using the response surface methodology (RSM). Meanwhile, the effects of the concentration of cross-linker, initiator, bentonite, and degree of neutralization of acrylic acid on WA were investigated. The SRNFWA was characterized by Fourier transform infrared (FTIR) spectroscopy, elemental analysis, and scanning electron microscopy (SEM). The results of SEM showed the undulant and coarse surface, facilitated the permeation of nutrition into the polymeric network. We also investigated the slow release property and release mechanism of the nitrogen from the network structure,