Tranexamic acid for patients with nasal haemorrhage (epistaxis)

Abstract

Analysis 1.3. Comparison 1 Tranexamic acid versus placebo plus usual care or usual care alone, Outcome 3 Severity of rebleeding: proportion of patients requiring blood transfusion within 10 days.

Tranexamic Acid in a Case Report of Life-threatening Nontraumatic Hemorrhage in Immune Thrombocytopenic Purpura

“… 11 It has also been studied for the treatment of epistaxis. 10 , 12 TXA is quickly becoming a standard of care in the treatment of adult trauma patients, with studies ongoing in pediatric trauma patients. 13 A few of these studies have shown a slightly higher risk for postoperative seizures; however, the majority of studies show that TXA has minimal side effects.…”

Thrombostatic Agents and Tissue Adhesives in the Emergency Department: Stopping the Bleeding, Closing the Wound, and Novel Applications

“…In another prospective study, FloSeal ® effectively controlled posterior bleeds in 8 of 10 patients whose initial packing failed [61]. Surgicel ® and Gelfoam ® are common conformable hemostatic materials and have been described in reviews or small case series as useful in nasal bleeding refractory to cautery [62]. These materials can be trimmed to an appropriate size and then applied directly to the bleeding source.…”

Tranexamic Acid for the Treatment of Epistaxis

“…The Cochrane Review discussed here included randomized controlled trials comparing tranexamic acid (TXA) in any formulation (e.g., delivered orally, intravenously, or topically) with usual care versus usual care with placebo, usual care with any other hemostatic agent, or usual care alone . The primary outcome was the proportion of patients with rebleeding within 10 days and significant adverse events (i.e., seizures, thromboembolic events).…”