Transabdominal fine needle biopsy from chorionic villi in the first trimester

Smidt‐Jensen, Steen; Hahnemann, Niels

doi:10.1002/pd.1970040302

Cited by 110 publications

(27 citation statements)

References 11 publications

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“…Most commonly, a small sample of chorionic villi is aspirated through a flexible catheter which is passed through the cervix under sonographic guidance (21). Alternatively, an aspiration needle can be passed transabdominally (22). As with cells obtained via amniocentesis, the diagnosis of hereditable disorders may be made by enzyme assays, chromosome number or abnormality, and DNA analysis (Table 5) (23).…”

Section: Chorionic Villus Samplingmentioning

confidence: 99%

Physiologic Assessment of Fetal Compromise: Biomarkers of Toxic Exposure

Longo¹

1987

Environmental Health Perspectives

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Section: Chorionic Villus Samplingmentioning

confidence: 99%

Physiologic Assessment of Fetal Compromise: Biomarkers of Toxic Exposure

Longo¹

1987

Environmental Health Perspectives

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“…The CVS technique was performed in accordance with the trans abdominal CVS technique described by Smidt-Jensen and Hahne mann [4], Local anesthesia was used in the form of a salve (Emla, Astra, Sweden) applied cutaneously on the abdomen about 30 min before the start of the sampling procedure. Under continuous ultra sound guidance (Kretz, Combisone), the 18-gauge.…”

Section: Methodsmentioning

confidence: 99%

Risk Evaluation in a Small Series of Transabdominal Chorionic Villus Sampling

Bergman

Claesson

Mark

1991

Gynecol Obstet Invest

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Previous reports have suggested that the fetal loss rate with transcervical chorionic villus sampling was high in the initial 100–300 procedures performed. In a consecutive series of 155 patients with first-trimester transabdominal chorionic villus sampling (CVS), we observed a total fetal loss rate of 8.4%, and a loss rate not attributable to induced abortion or cytogenetic abnormality of 3.2%. Our results demonstrate that transabdominal CVS in the first trimester of pregnancy is a safe method of prenatal diagnosis.

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“…Both approaches are done under ultrasonographic control with strict observance of the rules of asepsis-antisepsis [5,6]. With suitable technical equipment and devices, an expert with sufficient practical experience can decide on the method of sampling on a case-by-case basis taking into consideration the particular circumstances (anatomical location of the chorion frondosum, possible cervical or vaginal infections).…”

Section: Introductionmentioning

confidence: 99%

Chorionic Villus Sampling: A 15-Year Experience

Papp¹,

Beke²,

Mezei³

et al. 2002

Fetal Diagn Ther

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The authors describe experiences gained over the period of 1984–1999 at two medical centers with chorionic villus sampling (CVS). Altogether 1,149 CVSs had been performed between the 10th and 32nd gestational weeks. Prior to 1993 the transcervical approach (TC-CVS), after 1994 the transabdominal method (TA-CVS) was used. Analysis of data collected within the framework of this study was based on the following factors: indications for sampling, complications and incidence of pregnancy loss. 91.6% of the CVSs were carried out for the purposes of cytogenetic examination of the fetus. Over the past few years an increasing number of procedures had been carried out for molecular-genetic tests (7.6% of the total number of cases). Though the primary indication for cytogenetic tests was the advanced age of the mother, a remarkable increase in the number of samplings had taken place for the purpose of examining ‘suspicious ultrasound findings’, minor anomalies detected by ultrasound. In this group the proportion of pathological cases was significantly higher (14%) than in all the other samplings, carried out for other indications. This data in itself underlines the importance of ultrasound screening performed in the 18–20th weeks of gestation. Over the first half of the period being reviewed (1984–1993, TC-CVS), a fetal loss of 4.8% occurring within 3 weeks from the date of sampling, dropped to 1.7% in the period subsequent to year 1994 (TA-CVS). In cases of TA-CSV, both the complications and spontaneous abortions were fewer. In 74.1% of the cases studied, birth had taken place after the 37th week of gestation. Premature births (6.4%) and stillbirth rate (1.1%) did not exceed normal rates observed in the general population. On the basis of our results, it is safe to say that in prenatal diagnosis, TA-CVS is a real alternative method of mid-trimester amniocentesis and it is recommended for use at any stage of the pregnancy.

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Transabdominal fine needle biopsy from chorionic villi in the first trimester

Cited by 110 publications

References 11 publications

Physiologic Assessment of Fetal Compromise: Biomarkers of Toxic Exposure

Physiologic Assessment of Fetal Compromise: Biomarkers of Toxic Exposure

Risk Evaluation in a Small Series of Transabdominal Chorionic Villus Sampling

Chorionic Villus Sampling: A 15-Year Experience

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