Transaminase Activities of Gingiva in Scurvy

Relationship Between Crevicular Aspartate Aminotransferase Levels and Periodontal Disease Progression

“…1 Biochemical markers in gingival crevicular fluid (GCF) associated with the anatomic events of periodontitis have been investigated as potential methods to identify and predict future disease progression. [2][3][4][5] One host-derived enzyme that has been extensively studied in both animal [6][7][8] and human [9][10][11][12][13] investigations is aspartate aminotransferase (AST). The results of these studies indicate that elevated levels of AST are identified at sites experiencing gingival inflammation, 10,12 sites exhibiting a history of past attachment loss, and at sites actively undergoing disease progression.…”

Association of gingival crevicular fluid and serum intracytoplasmic enzyme levels in periodontally healthy homozygous (major) β‐thalassemia patients

“…To assess tissue necrosis in b-thalassemia major patients, as in other areas of medicine (La Due et al 1954, DeRitis et al 1957, Wroblewski & Gregory 1961, Nakamura et al 1967, Bauer et al 1974, Wallach 1978, Adolph & Lorenz 1982 Lazaros E. Tsalikis 1 , Eleftherios G. Kaklamanos 2 , Smaragda Kavadia-Tsatala 3 , Eleni Chasapopoulou 4 and Ifigenia Pidonia-Manika 5 1982), lactate dehydrogenase (LDH), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) have been widely used, because they comprise soluble intracytoplasmic enzymes, confined to the cytoplasm but released on cell death. Serum LDH is mildly elevated because of ineffective erythropoiesis and has been used to monitor intramedullary hemolysis (Toren et al 1996).…”