Transcortin. Comparison of the cortisol-binding globulin from human and cavian plasma

Slaunwhite, W. Roy; Schneider, Sara L.

doi:10.1021/bi00787a020

Biochemistry

1971

DOI: 10.1021/bi00787a020

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Transcortin. Comparison of the cortisol-binding globulin from human and cavian plasma

W. Roy Slaunwhite¹,

Sara L. Schneider²

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1973

1984

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Cited by 37 publications

References 23 publications

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Chemie und Bedeutung des Kohlenhydrat‐Anteils menschlicher Serum‐Glykoproteine

Heide

Schwick

1973

Angewandte Chemie

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Die Glykoproteine üben als Transportproteine, Inhibitoren, Enzyme, Hormone, Komplementfaktoren und Immunglobuline wichtige biologische Funktionen aus. Ihre Chemie ist durch einige Regeln gekennzeichnet. So können nur Asparagin, Threonin oder Serin die Oligosaccharid‐Gruppen tragen; bei der N‐Acylglykosylamin‐Bindung unter Beteiligung von Asparagin liegt in der Peptidkette stets die Gruppierung Asn‐X‐Thr oder Asn‐X‐Ser vor. Beim Molekulargewicht der Glykoproteine. ihrem Kohlenhydrat‐Gehalt und den relativen Anteilen der einzelnen Zucker findet man allerdings kaum Übereinstimmungen. Die biologische Bedeutung des Kohlenhydrat‐Anteils ist noch ungeklärt, doch zeichnet sich eine Vorstellung von der Rolle der leicht entfernbaren Neuraminsäure ab.

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Chemie und Bedeutung des Kohlenhydrat‐Anteils menschlicher Serum‐Glykoproteine

Heide

Schwick

1973

Angewandte Chemie

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Chemistry and Significance of the Carbohydrate Moieties of Human Serum Glycoproteins

Heide

Schwick

1973

Angew. Chem. Int. Ed. Engl.

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The glycoproteins exercise important biological functions as transport proteins, inhibitors, enzymes, hormones, complement factors, and immunoglobulins. Their chemistry is characterized by a number of rules. Thus only asparagine, threonine, or serine can carry the oligosaccharide groups; for the N‐acylglycosylamine linkage involving asparagine, the grouping Asn‐X‐Thr or Asn‐X‐Ser is always present in the peptide chain. However, practically no agreement is found in the molecular weights of the glycoproteins, their carbohydrate contents, and the relative contents of the‐various sugars. The biological significance of the carbohydrate fraction has not yet been explained, but some idea of the part played by the easily removable neuraminic acid is being formed.

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Fluid Shifts and Other Factors Affecting Plasma Protein Binding of Prednisolone by Equilibrium Dialysis

Boudinot

Jusko

1984

Journal of Pharmaceutical Sciences

139

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Transcortin. Comparison of the cortisol-binding globulin from human and cavian plasma

Cited by 37 publications

References 23 publications

Chemie und Bedeutung des Kohlenhydrat‐Anteils menschlicher Serum‐Glykoproteine

Chemie und Bedeutung des Kohlenhydrat‐Anteils menschlicher Serum‐Glykoproteine

Chemistry and Significance of the Carbohydrate Moieties of Human Serum Glycoproteins

Fluid Shifts and Other Factors Affecting Plasma Protein Binding of Prednisolone by Equilibrium Dialysis

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