2018
DOI: 10.3390/brainsci8050081
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Transcranial Direct Current Stimulation (tDCS): A Promising Treatment for Major Depressive Disorder?

Abstract: Background: Transcranial direct current stimulation (tDCS) opens new perspectives in the treatment of major depressive disorder (MDD), because of its ability to modulate cortical excitability and induce long-lasting effects. The aim of this review is to summarize the current status of knowledge regarding tDCS application in MDD. Methods: In this review, we searched for articles published in PubMed/MEDLINE from the earliest available date to February 2018 that explored clinical and cognitive effects of tDCS in … Show more

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Cited by 99 publications
(76 citation statements)
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“…According to cerebral imaging, the dorsolateral prefrontal cortex (DLPFC) has an important role in the pathophysiology of mood disorders (Cosmo et al, 2015). Recently, tDCS has been recommended for treatment of depression with the anode over the left DLPFC (Bennabi and Haffen, 2018).…”
Section: Effects On Depression and Anxietymentioning
confidence: 99%
“…According to cerebral imaging, the dorsolateral prefrontal cortex (DLPFC) has an important role in the pathophysiology of mood disorders (Cosmo et al, 2015). Recently, tDCS has been recommended for treatment of depression with the anode over the left DLPFC (Bennabi and Haffen, 2018).…”
Section: Effects On Depression and Anxietymentioning
confidence: 99%
“…This mechanistic understanding can help design current waveforms for neurons that exhibit TI stimulation, and also help classify which neuron-types may or may not exhibit TI stimulation. 1 Transcranial electrical stimulation (TES) is widely used in neuroscientific studies and clinical treatments [1], [2], [3]. Several studies have examined techniques for improving resolution of TES, including using techniques from optimization.…”
mentioning
confidence: 99%
“…Specifically, lower age, female gender, a lower BDI baseline score, and higher MWT score were associated with increased training success. Initially, the pattern may seem less plausible with regard to reported antidepressant effects of atDCS [111]). However, although MCI patients scored higher in BDI compared to HE, the scores did not reach the threshold for clinical depression and may accordingly differ with respect to tonic cortical activation/excitation from depressed patients resulting in a different atDCS response.…”
Section: Variability Of Atdcs Effectsmentioning
confidence: 99%