Transcranial Doppler Ultrasound Study of Brain Hemispheric Functional Specialization: A Review of Foreign Literature

Objective. Creation of the audit methodology for іntensity of restoration of the energy-structure status while application of technologies of personified intensive therapy in superacute and acute periods of ischemic cerebral stroke. Materials and methods. The work was performed on the base of the audit results, obtained for intensity of the energy-structure status restoration in 134 patients, suffering the ischemic cerebral stroke, who stayed in the intensive therapy wards of Department of Neurology. In accordance to intensity of restoration of the energy-structure status the technologies of personified intensive therapy were applied: the homeostasis guaranteeing in eubiotic state; energy-protection in hypoergic dysfunction; energy-resuscitation in hypoergic damage; energy-correction in hypoergic insufficiency. Results. Using the achievement of the main physiological targeted indices of organism in the patients, suffering the ischemic cerebral stroke (the arterial blood saturation by the oxygen, average arterial pressure, the heart rate and central venous pressure), it became possible to improve the treatment results. Clinical application of the proposed method of personified restoration of the energy-structure status have promoted to prevent further development of the vital activity disorders, what have had reduced the disability index in patients, suffering an ischemic cerebral stroke. Achievement of the indices targeted realized, using the methods of personified intensive therapy, constitutes a guarantee for the vital skills exclusion in patients, suffering an ischemic cerebral stroke. Conclusion. The clinical investigation conduction have permitted to elaborate the audit methodology for the energy-structure status restoration in the ischemic cerebral stroke and in accordance to intensity of restoration of the energy-structure status indices to apply the іnnovative technologies of personified intensive therapy.

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Methodology of audit for the intensity restoration of the energy-structural status in patients, suffering an ischemic cerebral stroke

Серіков

Смирнова²,

Shifrin

2021

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A new methodology for systemic audit of ischemic stroke in the most acute and acute periods of the disease

Smyrnova

Shifrin

Серіков

2021

Modern Medical Technology

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Purpose of the study. Create a methodology for systemic audit of ischemic stroke (IS) in the most acute and acute periods of the disease. Materials and methods. The clinical study included 328 patients with IS (mean age 71,26 ± 0,44 years), who were in the intensive care unit of the neurology department in the most acute and acute periods of the disease. There were 147 men (mean age 69,80 ± 0,66 years), women 181 (mean age 72,45 ± 0,58 years). According to the intensity of ESST disorders, assistive technologies of personalized intensive therapy (IT) were developed, such as homeostasisprovision for eubiotic state, energy-protection for hypoergic dysfunction, energy-resuscitation for hypoergic damage, energy-correction for hypoergic insufficiency, status-protection for hyperergic dysfunction, status-resuscitation for hyperergic damage, status-correction for hyperergic insufficiency. Results. The main parameters of energystructural status (ESST), which characterize the stabilization of the general condition of patients in the most acute and acute periods of IMI, such as cardiac index (CI) in the range of 2,99–3,79 L×min-1 × m-2, oxygen delivery (DO ) at the level of 415–514 ml × min-1 × m-2; oxygen consumption (VO2) in the range of 130–160 ml × min-1 × m-2; basal metabolism (BM) in the range of 916–1134 kcal × day-1 × m-2 and specific peripheral vascular resistance (SPVR) in the range of 29–36 conditional unit. Conclusion. The conducted clinical research allowed to develop assistive technologies of personalized IT, which were used depending on the severity of energy-structural disorders in patients with IS. The use of personalized IT technologies, in accordance with the intensity of ESST recovery, has reduced mortality, the number of complications and the length of stay of patients with IS in the intensive care units of the neurology department.

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Transcranial Doppler Ultrasound Study of Brain Hemispheric Functional Specialization: A Review of Foreign Literature

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Methodology of audit for the intensity restoration of the energy-structural status in patients, suffering an ischemic cerebral stroke

Methodology of audit for the intensity restoration of the energy-structural status in patients, suffering an ischemic cerebral stroke

A new methodology for systemic audit of ischemic stroke in the most acute and acute periods of the disease

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