Purpose: Transdisciplinary research has the potential to enhance the real-world impact of the field of aging and technology. This is a context-driven and problem-focused approach to knowledge production that involves collaboration across scientific disciplines and academic and non-academic sectors. To sustain broader implementation of this approach, a scoping review was conducted on the impact of this approach on research processes, outcomes, and uptake. Materials and Methods: A systematic search was conducted of aging, health/medicine, and technology literatures indexed in three electronic data bases (Medline/OVID, EBSCO, ProQuest) from Jan 1, 2005 to Dec 31, 2015. Search terms included 3 themes: (1) transdisciplinarity; (2) research outcomes; and (3) social change. Results: Twenty articles met the inclusion criteria. We found that a transdisciplinary approach to research enhances integration of diverse knowledges, scientific and extra-scientific outcomes, capacity to engage in translational research, and the uptake of research knowledge. We also identified a number of facilitators and barriers to successful implementation of this approach. No articles evaluating transdisciplinary research specifically in the context of aging and technology were found. Conclusions: Adoption of transdisciplinary research in aging and technology may foster greater uptake of technological innovation in the real-world by supporting integration of diverse knowledges and enhancing engagement of experiential and non-academic stakeholders in the research and development process. However, supporting successful implementation of this approach requires investment of personal and structural resources. More research is also needed to better understand the evidence base on the adoption of this approach in aging and technology projects.