Veno -venous extracorporeal membrane oxygenation (VV-ECMO) is an extracorporeal respiratory support used as therapeutic option in patients affected
Abbreviations: VV-ECMO-Veno-venous Extracorporeal Membrane Oxygenation, ARDS-Acute Respiratory Distress Syndrome, BMI-Body Mass Index, CT-Computed Tomography, ABG-Arterial blood gases, WBC-White Blood Count, CRP-C-Reactive Protein, TEE-Transesophageal Echocardiographic, APTT-Activated Partial Thromboplastin Time, SIMV-Synchronized,Intermittent Mandatory Ventilation, PS-Pressure Support, PEEPPositive end-expiratory pressure, RR-Respiratory Rate
MAIN BODY TEXTA 49-year-old male affected by severe obesity (BMI 40.1 Kg/m 2 ), sleep apnea syndrome and type II diabetes mellitus, developed severe ARDS by influenza A, which was not responsive to maximal ventilatory support and to cycles of prone positioning in a secondary hospital. After 48 hours, the patient was recovered to our Cardiovascular Intensive Care Unit to perform VV-ECMO treatment.Upon admission, the chest Computed Tomography (CT) scan showed an extensive case of ARDS with pulmonary infiltrates affecting all lung fields (Figure 1). The Murray Score (1) was 3.5 and arterial blood gases (ABG) showed: pH 7.33, pO 2 40 mmHg, pCO 2 51 mmHg, HCO3 25 mmol/L, pO 2 /FiO 2 ratio 172 and evidence of mild tissue hypoxia (Lactate 3.4, SVO2 74.7, Table 1). Laboratory values revealed white blood count (WBC) 4.420 x 10 9 /l,C-Reactive Protein (CRP) 8,45 mg/dl, the cultural samples were collected and both the tracheal aspirate and the nasal swab tested were positive to Influenza A (not type H1N1). The patient had no other sign of systemic failure (PA 165/50 mmHg, HR 95 beats/min, diuresis 70 ml/h).