Transfer rates of toxic metals during decoction preparation from hebal medicines and safety evaluation of the final decoction products

Kim, Dong-Gyu; Lee, Sung-Deuk; Yu, In-Sil; Jung, Kyomin; Park, Seung-Kook

doi:10.1007/s10068-015-0098-8

Cited by 9 publications

(2 citation statements)

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“…In another work, the following sequence of extraction efficiencies was observed (Cd: 53.1%, Pb: 47.5%, Zn: 39.02%, Mn: 19.98%, Cu: 14.4%, and Fe: 10.09%) [ 26 ]; the results for Cd, Pb, and Mn were in conflict with the results obtained in the present study. However, in agreement with results of the present study, a recent study showed that the extraction efficiencies for Pb and Cd from raw material of herbs to the infusion solutions were 4.3% and 4.1%, respectively [ 31 ]. In another related work, the extraction efficiencies of various metals from ten herbs were reported as Zn: 35%, Cu: 33%, Mn: 24%, and Fe: 6% [ 32 ].…”

Section: Discussionsupporting

confidence: 93%

The Hazard Content of Cadmium, Lead, and Other Trace Elements in Some Medicinal Herbs and Their Water Infusions

Ababneh

2017

International Journal of Analytical Chemistry

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54 samples belonging to 23 herbal species (15 individuals and 8 mixtures) were analyzed for their contents of heavy metals in the raw materials and in their water infusions. Trace and toxic elements in these samples were determined by using inductively coupled plasma-atomic emission spectrometry (ICP-OES) following acid digestion. The order of decreasing mean metal concentrations in raw materials (mg/kg) was found to be as follows: Fe (440) > Mn (162) > Zn (45.8) > Cu (12) > Pb (10.4) > Ni (5.4) > Cr (2.9) > Co (0.91) > Cd (0.5). It was found that 21% of the analyzed samples contain both Cd and Pb above their permissible limits. However, the infusions produced from these plants were found to contain fewer amounts of metals than the raw materials. Studied metals had the following mass transfer percentages to the infusion solutions (Fe: 3.5%, Cd: 14%, Cr: 15%, Pb: 20%, Co: 29%, Ni: 31%, Zn: 36%, Cu: 48%, and Mn: 53%). The estimated daily intake calculated for the toxic elements Pb and Cd through the consumption of herbal infusions was far below the tolerable daily intake set by the World Health Organization (WHO).

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Section: Discussionsupporting

confidence: 93%

The Hazard Content of Cadmium, Lead, and Other Trace Elements in Some Medicinal Herbs and Their Water Infusions

Ababneh

2017

International Journal of Analytical Chemistry

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“…The quantity of contaminants can be changed in manufacturing process for final products. A study presented the significantly low transfer rates of toxic metals (10.5% for As, 4.1% for Cd, 4.3% for Pb, and 2.7% for Hg) after decoction process of herbal formulae [ 42 ]. One study reported a 5.3% detection rate of residual pesticides and 0.9% excess MRLs rate among 1565 medicinal herbs [ 43 ], and another study presented the 12.5% excess MRLs rate among136 medicinal herbals [ 44 ] in Korea.…”

Section: Discussionmentioning

confidence: 99%

Monitoring heavy metals, residual agricultural chemicals and sulfites in traditional herbal decoctions

Lee

Kim

et al. 2017

BMC Complement Altern Med

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BackgroundAsian traditional herbal preparations are frequently considered for the contamination with undeclared toxic or hazardous substances. The aim of this study was to determine the toxic heavy metals, pesticides and sulfur dioxide in decoctions that is a common form of final utilization in Korea.MethodsA total of 155 decoctions composed of multi-ingredient traditional herbs were randomly sampled from Seoul in Korea between 2013 and 2014. For each decoction, the concentrations of four heavy metals (arsenic, cadmium, lead and mercury), 33 pesticides and sulfur dioxide were analyzed using inductively coupled plasma mass spectrometry (ICP-MS), mercury analyzer, gas chromatography/nitrogen phosphorous detector (GC/NPD), gas chromatography/micro electron capture detector (GC/μECD), and Monier-Williams method respectively.ResultsOne hundred fifty-two of One hundred fifty-five decoctions (98.1%) contained one of three heavy metals (96.1% for As, 97.4% for Cd, and 90.3% for Pb, 0.0% for Hg). Their average concentrations (77.0 ± 79.7 ug/kg for As, 20.4 ± 23.7 ug/kg for Cd, and 68.8 ± 76.5 ug/kg for Pb) were approximately 20% of the maximum allowable limits of vegetable or ginseng beverage described in the Korean Food Standard Codex while their 95th percentile concentrations were below than the guideline for them. None of 33 pesticides was detected in 155 decoction samples, and only one sample showed over limit of detection for residual sulfites.ConclusionsThis study support that the contained status of toxic heavy metals, pesticides and sulfur dioxide in herbal decoctions are currently within safe level in Korea, and provide a reference data for the further studies focused on the safety herbal preparations.Electronic supplementary materialThe online version of this article (doi:10.1186/s12906-017-1646-y) contains supplementary material, which is available to authorized users.

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Evaluation of Trace Element Contamination and Health Risks of Medicinal Herbs Collected from Unpolluted and Polluted Areas in Sichuan Province, China

Gao

Zhang

Uwiringiyimana

et al. 2021

Biol Trace Elem Res

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Transfer rates of toxic metals during decoction preparation from hebal medicines and safety evaluation of the final decoction products

Cited by 9 publications

References 8 publications

The Hazard Content of Cadmium, Lead, and Other Trace Elements in Some Medicinal Herbs and Their Water Infusions

The Hazard Content of Cadmium, Lead, and Other Trace Elements in Some Medicinal Herbs and Their Water Infusions

Monitoring heavy metals, residual agricultural chemicals and sulfites in traditional herbal decoctions

Evaluation of Trace Element Contamination and Health Risks of Medicinal Herbs Collected from Unpolluted and Polluted Areas in Sichuan Province, China

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